Every week we review the most recent publications in women’s mental health, covering topics related to premenstrual symptoms, perinatal mood and anxiety disorders, use of medications in pregnant and breastfeeding women, perinatal substance use, and menopausal mental health.

For more detailed descriptions of many of these topics, you can sign up to receive our weekly CWMH NEWSLETTER which comes out every Thursday.

Ruta Nonacs, MD PhD


Associations Between Symptoms of Premenstrual Disorders and Polygenic Liability for Major Psychiatric Disorders.

Jaholkowski P, Shadrin AA, Jangmo A, Frei E, Tesfaye M, Hindley GFL, Haram M, Rahman Z, Athanasiu L, Bakken NR, Holen B, Fominykh V, Kutrolli G, Parekh P, Parker N, Rødevand L, Birkenæs V, Djurovic S, Frei O, O’Connell KS, Smeland OB, Tesli M, Andreassen OA. JAMA Psychiatry. 2023 Jul 1;80(7):738-742.

This genetic association study demonstrated that genetic liability for both affective spectrum disorder and major psychiatric disorders was associated with symptoms of premenstrual disorders, suggesting that premenstrual disorders have overlapping genetic foundations with major psychiatric disorders.

GABA-ergic Modulators: New Therapeutic Approaches to Premenstrual Dysphoric Disorder.

Sikes-Keilp C, Rubinow DR.

CNS Drugs. 2023 Aug;37(8):679-693.


No articles this week


Can psychological interventions prevent or reduce risk for perinatal anxiety disorders? A systematic review and meta-analysis.

Zimmermann M, Julce C, Sarkar P, McNicholas E, Xu L, Carr C, Boudreaux ED, Lemon SC, Byatt N.

Gen Hosp Psychiatry. 2023 Sep-Oct;84:203-214.

Interventions developed for perinatal anxiety were more effective than interventions to prevent perinatal depression. Psychological interventions show promise for reducing perinatal anxiety symptom severity, though interventions specifically targeting anxiety are needed.

Understanding Perinatal Depression Care Gaps by Examining Care Access and Barriers in Perinatal Individuals With and Without Psychiatric History.

McNicholas E, Boama-Nyarko E, Julce C, Nunes AP, Flahive J, Byatt N, Moore Simas TA. J Womens Health (Larchmt). 2023 Aug 16.

Development of the Edinburgh Postnatal Depression Scale-United States: An Updated Perinatal Mental Health Screening Tool Using a Respectful Care and Trauma-Informed Approach.

Moyer SW, Kinser PA, Nunziatio JD, Holmes CM, Salisbury AL.

J Womens Health (Larchmt). 2023 Aug 14.

The Edinburgh Postnatal Depression Scale-United States (EPDS-US) is an adapted version of the EPDS, that is inclusive and easy to understand for U.S. populations and incorporates a trauma-informed approach to perinatal mental health (PMH).


No articles this week


The prevalence and risk factors of suicidal ideation in women with and without postpartum depression.

Chen C, Okubo R, Okawa S, Hagiwara K, Mizumoto T, Higuchi N, Nakagawa S, Tabuchi T.

J Affect Disord. 2023 Nov 1;340:427-434.

Although with a low prevalence, SI occurs in women without postpartum depression, which has unique risk factors indicating distinct psychopathological mechanisms. These findings call for tailored SI intervention strategies according to whether postpartum depression is present or not.

Randomized controlled trial to prevent postpartum depressive symptomatology: An infant carrier intervention.

Little EE, Bain L, Hahn-Holbrook J.

J Affect Disord. 2023 Nov 1;340:871-876.

Participants in the intervention group reported using an infant carrier significantly more often than the control group. The intervention group reported fewer depressive symptoms at 6-weeks postpartum than the control group.

Prenatal Exposure to Nonpersistent Environmental Chemicals and Postpartum Depression.

Jacobson MH, Hamra GB, Monk C, Crum RM, Upadhyaya S, Avalos LA, Bastain TM, Barrett ES, Bush NR, Dunlop AL, Ferrara A, Firestein MR, Hipwell AE, Kannan K, Lewis J, Meeker JD, Ruden DM, Starling AP, Watkins DJ, Zhao Q, Trasande L; Environmental Influences on Child Health Outcomes Consortium.

JAMA Psychiatry. 2023 Sep 20:e233542.

Exposure to synthetic environmental chemicals found in plastics and personal care products, such as phthalates, were associated with increased risk of PPD.

The Role of Parenting Stress as a Mediator in the Relationship Between Postpartum Depressive Symptoms and Early Childhood Internalizing Behaviour.

Semeniuk D, Boerner KE, Brain U, Ryan D, Oberlander TF.

Child Psychiatry Hum Dev. 2023 Sep 8.

The relationship between higher postpartum mood symptoms at 3 months and increased internalizing behavior at 3 years of age was mediated by increased reports of parenting stress at 6 months.

Predictors of Postpartum Depression Among Women with Low Incomes in the United States.

Lau E, Adams YJ.

MCN Am J Matern Child Nurs. 2023 Aug 17.

Financial insecurity and alcohol use were positively associated with postpartum depression, whereas level of education and reported physical health were negatively associated with postpartum depression.

Posttraumatic Growth after Postpartum Psychosis.

Beck CT, Twomey T.

MCN Am J Matern Child Nurs. 2023 Aug 17.

Staying Up to Date With Evolving Postpartum Depression Pathophysiology and Treatment Research.

Deligiannidis KM, Vaughn R.

J Clin Psychiatry. 2023 Aug 14;84(4):sagppd3003sho.


No articles this week


No articles this week


Prenatal environmental adversity and child neurodevelopmental delay: the role of maternal low-grade systemic inflammation and maternal anti-inflammatory diet.

Wang H, Yin W, Ma S, Wang P, Zhang L, Li P, Shao Z, Chen X, Zhu P.

Eur Child Adolesc Psychiatry. 2023 Aug 18.

Increased systemic inflammation through mid- and late pregnancy mediates the association between prenatal environmental adversity and child neurodevelopmental delay.

Maternal-infant bonding and partner support during pregnancy and postpartum: Associations with early child social-emotional development.

de Waal N, Boekhorst MGBM, Nyklí?ek I, Pop VJM.

Infant Behav Dev. 2023 Aug;72:101871.

An emotional connection between mother and child originates in pregnancy and that experiencing positive feelings towards the fetus promotes positive maternal-infant bonding after birth and social-emotional capacities of the child.


Relationship Between Parental Postnatal Distress and 5-Year Mental Health Outcomes of Children Born at <30 Weeks and at Term.

Yates R, Treyvaud K, Lee KJ, Doyle LW, Cheong JLY, Pace CC, Spittle AJ, Spencer-Smith M, Anderson PJ.

J Dev Behav Pediatr. 2023 Sep 1;44(7):e455-e462.

Children born <30 weeks’ gestation showed more mental health symptoms than their term-born peers at age 5 years. Maternal postnatal distress was associated with poorer child mental health across both groups, reinforcing the need for early identification and support of mental health distress in the postnatal period to improve longer-term child well-being.


No articles this week


No articles this week

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