Bipolar Disorder

Accumulating Data on the Reproductive Safety of Second-Generation, Atypical Antipsychotics, But Still Not Enough

In a cohort of 351 children exposed to second generation antipsychotic during pregnancy, the risk of major congenital malformations did not differ from a comparison group of non-exposed children.

Essential Reads: Lithium and Breastfeeding

Because women with bipolar disorder are at high risk for relapse during the postpartum period, we typically recommend that women continue treatment with lithium throughout the postpartum period.  While this intervention clearly decreases risk for postpartum psychiatric illness, the use of lithium while breastfeeding presents certain challenges.  

Using the WHIPLASHED Mnemonic to Distinguish Unipolar from Bipolar Depression

Women with bipolar disorder (BD) are at extremely high risk for postpartum psychiatric illness, including postpartum psychosis.  While the American College of Obstetrics and Gynecology now recommends that all women be screened for depression [...]

PCOS Carries Increased Risk for Bipolar Disorder, Risk Reduced with Metformin

Polycystic Ovarian Syndrome (PCOS) is the most common endocrine-related dysfunction in women of reproductive age.  Multiple studies have observed a higher prevalence of psychiatric illness, including depressive disorders, anxiety disorders, and bipolar disorder in [...]

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