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Drawing on current research and clinical expertise, these articles address emerging trends, treatment considerations, and the complexities of care across the reproductive lifespan.

In this North American cross-sectional study, higher exposure to early life adversities was associated with a higher lifetime prevalence of physician-diagnosed PCOS/PMOS. The findings add to growing evidence that childhood adversities may have lasting effects on reproductive health.
Women with PMOS have significantly higher rates of depression and anxiety. Routine screening and integrated care are essential for improving psychiatric and reproductive outcomes.
Folic acid supplementation before and during early pregnancy substantially reduces the risk of neural tube defects. Emerging research suggests that folic acid may have beneficial effects on neurodevelopment that extend beyond the first trimester. We review the evidence on the timing of folic acid supplementation and findings from the FASSTT randomized controlled trial, which examined whether supplementation during the second and third trimesters was associated with improved cognitive outcomes in children.
Folic Acid Awareness Week (Sept 13-19, 2026) focuses on the importance of daily folic acid supplements for women to prevent birth defects, as diet alone is often insufficient.

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