Lithium use during pregnancy was associated with an increased risk of preterm birth and large for gestational age infants.
This meta-analysis is reassuring regarding risk for malformations in children exposed prenatally to oxcarbazepine; however, we still need more data to fully assess reproductive safety.
Lamotrigine is detected in the breast milk and in the serum of the nursing infant; however, the risk of adverse events is very low.
Given limited data on the reproductive safety of oxcarbazepine, we would recommend using alternate medications during pregnancy, when possible.
While the use of lithium has been in decline over the last 20 years, lithium continues to be a useful and highly effective mood stabilizer for women with bipolar disorder, especially those with a history [...]
You Asked: Should Women Taking Lamotrigine (Lamictal) Use Higher Dose of Folic Acid When Planning for Pregnancy?
We have really enjoyed our weekly virtual rounds. It’s been a great opportunity to meet other perinatal psychiatrists in the community, and discussions with new people always brings up interesting clinical questions. Last week [...]
For women with bipolar disorder, choosing whether to maintain or discontinue treatment with a mood stabilizer during pregnancy is challenging. This is a process which requires careful and thoughtful consideration, weighing the risk of adverse [...]
May 1, 2019 from ObGynNews Publish date: May 1, 2019 By Lee S. Cohen, MD Careful management of bipolar disorder during pregnancy is critical because for so many patients with this illness, the road to emotional [...]
EURAP is an international registry for antiepileptic drugs and pregnancy. At its inception in 1999, it included only European countries but EURAP has grown and now includes 42 countries from Europe, Australia, Asia, South America. [...]
Maintenance treatment with a mood stabilizer during pregnancy can significantly reduce the risk of relapse in women with bipolar disorder; however, many of the mood stabilizers commonly used in this setting, including lithium and [...]