A small phase 2a trial of GH001, an investigational psychedelic compound, found a rapid reduction in postpartum depression symptoms. Larger studies are needed to assess safety and durability.
Perinatal OCD is common but often missed by depression-only screens. Adding perinatal-specific anxiety and OCD tools can improve detection and guide targeted treatment.
Parents of infants in the NICU face high rates of depression, anxiety, stress, and trauma. Are we doing enough to identify their needs—and provide meaningful mental health support?
In recognition of Suicide Prevention Awareness Month: A Message from Dr. Lee Cohen
In this North American cross-sectional study, higher exposure to early life adversities was associated with a higher lifetime prevalence of physician-diagnosed PCOS/PMOS. The findings add to growing evidence that childhood adversities may have lasting effects on reproductive health.
Women with PMOS have significantly higher rates of depression and anxiety. Routine screening and integrated care are essential for improving psychiatric and reproductive outcomes.
Folic acid supplementation before and during early pregnancy substantially reduces the risk of neural tube defects. Emerging research suggests that folic acid may have beneficial effects on neurodevelopment that extend beyond the first trimester. We review the evidence on the timing of folic acid supplementation and findings from the FASSTT randomized controlled trial, which examined whether supplementation during the second and third trimesters was associated with improved cognitive outcomes in children.
For women who require treatment with quetiapine during pregnancy, the available reproductive safety data are generally reassuring. The largest body of evidence does not suggest a meaningful increase in major congenital malformations, while metabolic effects, particularly gestational diabetes, remain an important consideration.
If you or someone you know is in crisis, confidential support is available.
Reproductive psychiatrists Dr. Kristin Lasseter and Dr. Lee Cohen join Dr. Ruta and Allie for a conversation on the treatment and prevention of postpartum depression.
