Viguera, A. C., McElheny, S. A., Caplin, P. S., Kobylski, L. A., Rossa, E. T., Young, A. V., Gaccione, P., Góez-Mogollón, L., Freeman, M. P., & Cohen, L. S. Risk of Poor Neonatal Adaptation Syndrome Among Infants Exposed to Second-Generation Atypical Antipsychotics Compared to Antidepressants: Results From the National Pregnancy Registry for Psychiatric Medications. The Journal of clinical psychiatry84(1) (2023).

Freeman, M. P., Szpunar, M. J., Kobylski, L. A., Harmon, H., Viguera, A. C., & Cohen, L. S. Pregnancy outcomes after first-trimester exposure to buspirone: prospective longitudinal outcomes from the MGH National Pregnancy Registry for Psychiatric Medications. Arch Womens Ment Health (2022).

Szpunar, M. J., Freeman, M. P., Kobylski, L. A., Caplin, P. S., Gaccione, P., Viguera, A. C., Chitayat, D., Hernández-Días, S., & Cohen, L. S. Risk of major malformations in infants after first-trimester exposure to benzodiazepines: Results from the Massachusetts General Hospital National Pregnancy Registry for Psychiatric MedicationsDepression and Anxiety, 1– 9 (2022).

Viguera, A.C., Vanderkruik, R., Gaccione, P. et al. Breastfeeding practices among women taking second-generation antipsychotics: findings from the National Pregnancy Registry for Atypical AntipsychoticsArch Womens Ment Health (2021).

Viguera AC, Freeman MP, Góez-Mogollón L, et al. Reproductive safety of second-generation antipsychotics: updated data from the Massachusetts General Hospital National Pregnancy Registry for Atypical Antipsychotics. J Clin Psychiatry. 2021;82(4):20m13745.

Freeman, M.P., Viguera, A.C., Góez-Mogollón, L. et al. Reproductive safety of aripiprazole: data from the Massachusetts General Hospital National Pregnancy Registry for Atypical AntipsychoticsArch Womens Ment Health 24, 659–667 (2021).

Baker AS, Wales R, Noe O, Gaccione P, Freeman MP, Cohen LS. The Course of ADHD during PregnancyJournal of Attention Disorders. December 2020.

Joffe, H., de Wit, A., Coborn, J., Crawford, S., Freeman, M., Wiley, A., Athappilly, G., Kim, S., Sullivan, K.A., Cohen, L.S. and Hall, J.E., 2019. Impact of estradiol variability and progesterone on mood in perimenopausal women with depressive symptoms. The Journal of Clinical Endocrinology & Metabolism. 2019 Nov 6. dgz181

Freeman MP, Goez-Mogollon L, Sosinsky AZ, Church TR, McElheny SA, Viguera AC, Cohen LS. The impact of obesity on pregnancy outcomes among women with psychiatric disorders: Results from a prospective pregnancy registry. Journal of Psychosomatic Research. 2019; 123:109735.

Raffi ER, Nonacs R, Cohen LS. Safety of Psychotropic Medications During Pregnancy. Clinics in Perinatology. 2019; 46:215-234.

Freeman MP, Sosinsky AZ, Góez-Mogollón L, Savella GM, Moustafa D, Viguera AC, Cohen LS. Gestational weight gain and pre-pregnancy body mass index associated with second-generation antipsychotic use during pregnancy. Psychosomatics. 2018 Mar – Apr;59(2):125-134. doi: 10.1016/j.psym.2017.09.002. Pubmed PMID: 29078988

Maki PM, Kornstein SG, Joffe H, Bromberger JT, Freeman EW, Athappilly G, Bobo WV, Rubin LH, Koleva HK, Cohen LS, Soares CN; Board of Trustees for The North American Menopause Society (NAMS) and the Women and Mood Disorders Task Force of the National Network of Depression Centers.. Guidelines for the evaluation and treatment of perimenopausal depression: summary and recommendations. Menopause. 2018 Oct;25(10):1069-1085. doi: 10.1097/GME.0000000000001174. PubMed PMID: 30179986.

Freeman MP, Claypoole LD, Burt VK, Sosinsky AZ, Moustafa D, Noe OB, Cheng LJ, Cohen LS. Course of major depressive disorder after pregnancy and the postpartum period. Depress Anxiety. 2018 Sep 7. doi: 10.1002/da.22836. [Epub ahead of print] PubMed PMID: 30192044.

Cohen LS, Góez-Mogollón L, Sosinsky AZ, Savella GM, Viguera AC, Chitayat D, Hernández-Díaz S, Freeman MP. Risk of Major Malformations in Infants Following First Trimester Exposure to Quetiapine. Am J Psychiatry. 2018 Aug 16:appiajp201818010098. doi: 10.1176/appi.ajp.2018.18010098. [Epub ahead of print] PubMed PMID: 30111186.

Freeman MP, Lee H, Savella GM, Sosinsky AZ, Marfurt SP, Murphy SK, Cohen LS. Predictors of Depressive Relapse in Women Undergoing Infertility Treatment. J Womens Health (Larchmt). 2018 Aug 1. doi: 10.1089/jwh.2017.6878. [Epub ahead of print] PubMed PMID: 30067141.

Freeman MP, Farchione T, Yao L, Sahin L, Taylor L, Huybrechts KF, Nonacs R, Sosinsky AZ, Viguera AC, Cohen LS. Psychiatric Medications and Reproductive Safety: Scientific and Clinical Perspectives Pertaining to the US FDA Pregnancy and Lactation Labeling Rule. J Clin Psychiatry. 2018 Jul 17;79(4). pii: 18ah38120. doi: 10.4088/JCP.18ah38120. PubMed PMID: 30153401.

Freeman MP, Góez-Mogollón L, McInerney KA, Davies AC, Church TR, Sosinsky AZ, Noe OB, Viguera AC, Cohen LS. Obstetrical and neonatal outcomes after benzodiazepine exposure during pregnancy: Results from a prospective registry of women with psychiatric disorders. Gen Hosp Psychiatry. 2018 May 29;53:73-79. doi: 10.1016/j.genhosppsych.2018.05.010. [Epub ahead of print] PubMed PMID: 29958100.

Park Y, Hernandez-Diaz S, Bateman BT, Cohen JM, Desai RJ, Patorno E, Glynn RJ, Cohen LS, Mogun H, Huybrechts KF. Continuation of Atypical Antipsychotic Medication During Early Pregnancy and the Risk of Gestational Diabetes. Am J Psychiatry. 2018 Jun 1;175(6):564-574. doi: 10.1176/appi.ajp.2018.17040393. Epub 2018 May 7. PubMed PMID: 29730938; PubMed Central PMCID: PMC5988929.

Mitchell CM, Srinivasan S, Plantinga A, Wu MC, Reed SD, Guthrie KA, LaCroix AZ, Fiedler T, Munch M, Liu C, Hoffman NG, Blair IA, Newton K, Freeman EW, Joffe H, Cohen L, Fredricks DN. Associations between improvement in genitourinary symptoms of menopause and changes in the vaginal ecosystem. Menopause. 2017 Dec 4. doi: 10.1097/GME.0000000000001037. [Epub ahead of print] PubMed PMID: 29206774.

Raffi E, Freeman MP. The etiology of premenstrual dysphoric disorder: five interwoven pieces. Current Psychiatry. 2017;9:20-28.

Panchaud A, Hernandez-Diaz S, Freeman MP, Viguera AC, MacDonald SC, Sosinsky AZ, Cohen LS. Use of atypical antipsychotics in pregnancy and maternal gestational diabetes. J Psychiatr Res. 2017 Dec; 95:84-90.

Freeman MP, Cheng LJ, Moustafa D, Davies A, Sosinsky AZ, Wang B, Petrillo LF, Hogan C, Cohen LS. Vortioxetine for major depressive disorder, vasomotor, and cognitive symptoms associated with the menopausal transition. Ann Clin Psychiatry. 2017 Nov;29(4):249-257.

Freeman MP, Sosinsky AZ, Goez-Mogollon L, Savella GM, Moustafa D, Viguera AC, Cohen LS.  Gestational Weight Gain and Pre-pregnancy Body Mass Index Associated With Second-Generation Antipsychotic Drug Use During Pregnancy.   Psychosomatics. 2017 Sep 21.

Suri R, Stowe ZN, Cohen LS, Newport DJ, Burt VK, Aquino-Elias AR, Knight BT, Mintz J, Altshuler LL. Prospective Longitudinal Study of Predictors of Postpartum-Onset Depression in Women With a History of Major Depressive Disorder. J Clin Psychiatry. 2017 Sep/Oct; 78(8):1110-1116

Sosinsky AZ, Freeman MP, Savella GM, Cheng LJ, Viguera AC, Cohen LS. Delusional Pregnancy Presenting to the Massachusetts General Hospital National Pregnancy Registry for Atypical Antipsychotics. J Clin Psychopharmacol. 2017 Aug;37(4):472-474.

Huybrechts KF, Hernández-Díaz S, Patorno E, Desai RJ, Mogun H, Dejene SZ, Cohen JM, Panchaud A, Cohen L, Bateman BT.  Antipsychotic Use in Pregnancy and the Risk for Congenital Malformations.  JAMA Psychiatry. 2016 Sep 1;73(9):938-46.

Freeman MP. Wishful thinking is not effective contraception: family planning, contraception, and safe prescribing. Journal of Clinical Psychiatry. 2016;77(4):523-524.

Patorno E, Huybrechts KF, Bateman BT, Cohen JM, Desai RJ, Mogun H, Cohen LS, Hernandez-Diaz S.  Lithium Use in Pregnancy and the Risk of Cardiac Malformations. N Engl J Med. 2017 Jun 8; 376(23):2245-2254

Cohen, LS, Nonacs, R. Neurodevelopmental Implications of Fetal Exposure to Selective Serotonin Reuptake Inhibitors and Untreated Maternal Depression Weighing Relative Risks. JAMA Psychiatry; 2016 November 1.

Joffe H, Crawford S, Freeman MP, White DP, Bianchi MT, Kim S, Economou N, Camuso J, Hall JE, Cohen LS.  Independent contributions of nocturnal hot flashes and sleep disturbance to depression in estrogen-deprived women. J Clin Endocrinol Metab; 2016 Oct;101(10):3847-3855.

Freeman MP, Sosinsky AZ, Moustafa D, Viguera AC, Cohen LS. Supplement Use by Women during Pregnancy: Data from the Massachusetts General Hospital National Pregnancy Registry for Atypical Antipsychotics. Arch Women’s Mental Health. 2016 Jun;19(3):437-41

Meyer F, Freeman MP, Petrillo L, Barsky M, Galvan T, Kim S, Cohen L, Joffe H.  Armodafinil for fatigue associated with menopause: an open-label trial.  Menopause. 2016 Feb;23(2):209-14.

Freeman MP. Psychotropic medication use during pregnancy: changes to the labeling system and the importance of exposure registries. Journal of Clinical Psychiatry. 2015;76(7):990-991.

Habecker E, Freeman MP. Awareness and management of obstetrical complications of depression. Current Psychiatry 2015;14(12):39-44.

Hogan C, Freeman MP. Adverse effects in the pharmacologic management of bipolar disorder during pregnancy. Psychiatric Clinics of North America. 39(3):465-475.

Cohen LS, Viguera AC, McInerny KA, Freeman MP, et al. Reproductive Safety of Second-Generation Antipsychotics: Current Data From the Massachusetts General Hospital National Pregnancy Registry for Atypical Antipsychotics. Am J Psychiatry. 2015 Oct 6.

Caan B, LaCroix AZ, Joffe H, Guthrie KA, et al.  Effects of estrogen and venlafaxine on menopause-related quality of life in healthy postmenopausal women with hot flashes: a placebo-controlled randomized trial.  Menopause. 2015 Jun; 22(6):607-15.

Joffe H, LaCroix AZ, Cohen L. Concern about the use of venlafaxine to treat vasomotor symptoms—reply. JAMA Intern Med. 2015 Apr;175(4):658-659.

Freeman MP, Cohen LS, McInerney K. Omega-3 Fatty Acids and Gestational Length in a High-Risk Psychiatric Population Due to Psychiatric Morbidity and Medication Exposure During Pregnancy. J Clin Psychopharmacol. 2014 Jul 8.

Freeman MP, Cohen LS, McInerney K. Omega-3 Fatty acids and gestational length in a high-risk psychiatric population due to psychiatric morbidity and medication exposure during pregnancy.  J Clin Psychopharmacol. 2014 Oct; 34(5):627-32.

Psaros C, Freeman M, Safren SA, Barsky M, Cohen LS. Discontinuation of antidepressants during attempts to conceive: A pilot trial of cognitive behavioral therapy for the prevention of recurrent depression. J Clin Psychopharmacol. 2014 Aug;34(4):455-60.

Cohen LS, Joffe H, Guthrie KA, Ensrud KE, Freeman M, Carpenter JS, Learman LA, Newton KM, Reed SD, Manson JE, Sternfeld B, Caan B, Freeman EW, Lacroix AZ, Tinker LF, Laforce CB, Larson JC, Anderson GL. Efficacy of omega-3 for vasomotor symptoms: a randomized controlled trial. Menopause. 2014;21(4):347-54.

Huybrechts KF, Palmsten K, Avorn J, Cohen LS, Holmes LB, Franklin JM, Mogun H, Levin R, Kowal M, Setoguchi S, Hernández-Díaz S. Antidepressant use in pregnancy and the risk of cardiac defects. N Engl J Med. 2014 Jun 19; 370(25):2397-407.

Psaros C, Freeman M, Safren SA, Barsky M, Cohen LS. Discontinuation of Antidepressants During Attempts to Conceive: A Pilot Trial of Cognitive Behavioral Therapy for the Prevention of Recurrent Depression. J Clin Psychopharmacol. 2014 Aug;34(4):455-60

Freeman MP. Perinatal psychiatry: an emerging specialty. Journal of Clinical Psychiatry 2014; 75(10):1086-1087. 

Joffe H, Guthrie KA, LaCroix AZ, et al. Low-Dose Estradiol and the Serotonin-Norepinephrine Reuptake Inhibitor Venlafaxine for Vasomotor Symptoms: A Randomized Clinical Trial. JAMA Intern Med. 2014 May 26; 174(7): 1058-66  

Cohen LS, Joffe H, Guthrie KA, et al. Efficacy of omega-3 for vasomotor symptoms treatment: a randomized controlled trial.  Menopause. 2014 Apr;21(4):347-54.

Freeman MP. Attention deficit/hyperactivity disorder (ADHD) and pregnancy. American Journal of Psychiatry. 2014;171(7):723-728.

Freeman MP, Toth TL, Cohen LS. Assisted reproduction and risk of depressive relapse: considerations for treatment. Annals of Clinical Psychiatry. 2013;25(4):283-288.

Freeman MP, Hirschberg AM, Wang B, Petrillo LF, Connors S, Regan S, Joffe H, Cohen LS. Duloxetine for Major Depressive Disorder and Daytime and Nighttime Hot Flashes Associated with the Menopausal Transition. Maturitas. 2013;75(2):170-4.

Sternfeld B, LaCroix A, Caan BJ, Dunn AL, Newton K, Reed SD, Guthrie KA, Booth-LaForce C, Sherman JK, Cohen LS, Freeman MP, Carpenter JS, Hunt JR, Roberts M, Ensrud KE. Design and Methods of a Multi-Site, Multi-Behavioral Treatment Trial for Menopausal Symptoms: The MsFLASH Experience. Contemporary Clinical Trials. 2013;35(1):25-34. 

Joffe H, Guthrie KA, Larson J, Cohen LS, Carpenter JS, Lacroix AZ, Freeman EW.  Relapse of vasomotor symptoms after discontinuation of the selective serotonin reuptake inhibitor escitalopram: results from the Menopause Strategies: Finding Lasting Answers for Symptoms and Health Research Network. Menopause. 2013 Mar; 20(3):261-268.

Freeman MP, Walker R, Laughren TP, Miller KK, Fava M. Female Reproductive Life Cycle and Hormones: Methodology to Improve Clinical Trials. J Clin Psychiatr., 2013;74(10):1018-21. PMC4096821.

Freeman MP, Joffe H, Cohen LS. Postpartum depression: Help patients find the right treatment, Current Psychiatry Nov 2012:14-21. 

Ensrud KE, Joffe H, Guthrie KA, et al.  Effect of escitalopram on insomnia symptoms and subjective sleep quality in healthy perimenopausal and postmenopausal women with hot flashes: a randomized controlled trial. Menopause. 2012 Aug;19 (8):848-855.

Gibson CJ, Joffe H, Bromberger JT, et al. Mood symptoms after natural menopause and hysterectomy with and without bilateral oophorectomy among women in midlife.Obstet Gynecol. 2012 May; 119(5):935-41.

Joffe H, Chang Y, Dhaliwal S, Hess R, Thurston R, Gold E, Matthews KA, Bromberger JT. Lifetime history of depression and anxiety disorders as a predictor of quality of life in midlife women in the absence of current illness episodesArch Gen Psychiatry. 2012 May; 69(5):484-92.

Rogines-Velo MP, Heberle AE, Joffe H.  Effect of medroxyprogesterone on depressive symptoms in depressed and nondepressed perimenopausal and postmenopausal women after discontinuation of transdermal estradiol therapy. Menopause. 2012 April; 19(4):471-5.

Freeman MP, Hibbeln JR, Silver M, Hirschberg AM, Wang B, Yule AM, Petrillo LF, Pascuilla E, Economou NI, Joffe H, Cohen LS. Omega-3 Fatty Acids for Major Depressive Disorder Associated with the Menopausal Transition: A Preliminary Open Trial. Menopause. 2011 Mar;18(3):279-84. 

Freeman EW, Guthrie KA, Caan B, Sternfeld B, Cohen LS, Joffe H, et al.  Efficacy of Escitalopram for Hot Flashes in Healthy Menopausal Women: A Randomized Controlled Trial. JAMA. 2011;305:267-274.

Joffe H, Petrillo LF, Koukopoulos A, Viguera AC, Hirschberg A, Nonacs R, Somley B, Pasciullo E, White DP, Hall JE, Cohen LS. Increased Estradiol and Improved Sleep, But Not Hot Flashes, Predict Enhanced Mood during the Menopausal Transition. J Clin Endocrinol Metab. 2011; 96(7): E1044-54 

Cohen LS, Wang B, Nonacs R, Viguera AC, Lemon EL, Freeman MP. Treatment of mood disorders during pregnancy and postpartum. Psychiatr Clin North Am. 2010; 33(2): 273-93.

Freeman MP, Mischoulon D, Tedeschini E, Goodness T, Cohen LS, Fava M, Papakostas GI. Complementary and alternative medicine (CAM) for major depressive disorder: a meta-analysis of patient characteristics, placebo response rates, and treatment outcomes relative to standard antidepressants. Journal of Clinical Psychiatry. 2010;71(6):682-8.

Joffe H, Petrillo L, Viguera A, Koukopoulos A, Silver-Heilman K, Farrell A, Yu G, Silver M, Cohen L. Eszopiclone improves insomnia, depressive and anxious symptoms in perimenopausal and postmenopausal women with hot flashes: A randomized, double-blinded, placebo-controlled cross-over trial. Am J Obstet Gynecol. 2010 Feb; 202(2):171.e1-171.e11.

Viguera AC, Cohen LS, Whitfield T, Reminick AM, Bromfield E, Baldessarini RJ. Perinatal use of anticonvulsants: differences in attitudes and recommendations among neurologists and psychiatrists. Arch Womens Ment Health. 2010 Jan 5.

Park ER, Chang Y, Quinn V, Regan S, Cohen L, Viguera A, Psaros C, Ross K, Rigotti N. The association of depressive, anxiety, and stress symptoms and postpartum relapse to smoking: A longitudinal study. Nicotine Tob Res. 2009 May 12.

Viguera AC, Emmerich AD, Cohen LS. Case 24-2008: A 35-year-old woman with postpartum confusion, agitation, and delusions. N Engl J Med. 2008; 359(5): 509-15.

Pearson KH, Nonacs RM, Viguera AC, Heller V, Petrillo LF, Brandes M, Hennen J, Cohen LS. Birth outcomes following prenatal exposure to antidepressants. J Clin Psychiatry 2007; 68(8):1284-1289.

Joffe H, Soares CN, Petrillo LF, Viguera AC, Somley BL, Koch JK, Cohen LS. Treatment of depression and menopause-related symptoms with the serotonin-norepinephrine reuptake inhibitor duloxetine. J Clin Psychiatry 2007; 68(6): 943-950.

Cohen LS. Treatment of bipolar disorder during pregnancy. J Clin Psychiatry 2007; 68(suppl 9):4-9.

Viguera AC, Whitfield T, Baldessarini RJ, Newport DJ, et al. Risk of Recurrence in Women With Bipolar Disorder During Pregnancy: Prospective Study of Mood Stabilizer Discontinuation. Am J Psychiatry 2007 December; 164:1817-1824.

Viguera AC, Newport DJ, Ritchie J et al. Lithium in Breastmilk and Nursing Infants: Clinical Implications. Am J Psychiatry. 2007 February: 164(2): 342-345.

Cohen L, Soares C, Vitonis A, Otto M, Harlow B. Risk for new onset of depression during the menopausal transition: The Harvard Study of Moods and Cycles. Arch Gen Psychiatry. 2006 April; 63:385-390

Cohen LS, Altshuler LL, Harlow BL, Nonacs R, et al. Relapse of major depression during pregnancy in women who maintain or discontinue antidepressant treatment: a preliminary prospective study. JAMA. 2004 October; 295(5):499-507.

Cohen LS, Altshuler LL, Stowe ZN, Faraone SV. Reintroduction of antidepressant therapy across pregnancy in women who previously discontinued treatment: A preliminary retrospective study. Psychother Psychosom 2004; 73(4):255-258

Cohen LS, Nonacs R, Viguera AC, Reminick A. Diagnosis and treatment of depression during pregnancy. CNS Spectr. 2004; 9(3):209-216.

Cohen LS. Gender specific considerations in the treatment of mood disorders in women across the life cycle. J Clin Psychiatry 2003; 64 (suppl. l5):18-34. 

Yonkers KA, Wisner KL, Stowe Z, Leibenluft E, Cohen L, Miller L, Manber R, Viguera A, Suppes T, Altshuler L.  Management of bipolar disorder during pregnancy and the postpartum period. Am J Psychiatry 2004 April; 161(4):608-620.

Joffe H, Cohen LS, Harlow BL. Impact of oral-contraceptive pill use on premenstrual mood: predictors of improvement and deterioration. Am J Obstet Gynecol. 2003; 189(6): 1523-1530.

Joffe H, Soares CN, Cohen LS. Assessment and treatment of hot flushes and menopausal mood disturbance. Psychiatr Clin N Am 2003; 26:563-580.

Viguera AC, Baldessarini RJ, Cohen LS, Nonacs R. Managing bipolar disorder during pregnancy: Weighing the risks and benefits. Canadian J Psych 2002; 47(5):426-436.

Viguera AC, Cohen LS, Bouffard S, Whitfield TH, Baldessarini RJ. Reproductive decisions by women with bipolar disorder after pre-pregnancy psychiatric consultationAm J Psychiatry 2002 December; 159: 2102–2104.

Freeman EW. Evaluation of a unique oral contraceptive (Yasmin) in the management of premenstrual dysphoric disorder. Eur J Contracept Reprod Health Care. 2002 Dec;7 Suppl 3:27-34; discussion 42-3.

Cohen LS, Viguera AC, Bouffard SM, Nonacs RM, Morabito C, Collins MH, Ablon JS. Venlafaxine in the treatment of postpartum depression. J Clin Psychiatry. 2001 Aug;62(8):592-6.

Viguera AC et al. Risk of recurrence of bipolar disorder in pregnant vs. nonpregnant women after discontinuing lithium maintenance. Am J Psychiatry. 2000 February; 157: 174-184.

Viguera AC, Nonacs R, Cohen LS, Tondo L, Murray A, Baldessarini RJ. Risk of recurrence of bipolar disorder in pregnant and nonpregnant women after discontinuing lithium maintenance. American Journal of Psychiatry. 157:179-84, 2000 February.

Cohen LS, Sichel DA, Robertson LM, Heckscher E, Rosenbaum JF. 1995. Postpartum prophylaxis for women with bipolar disorder. Am J Psychiatry. 152:1641-1645.

Cohen LS, Friedman JM, Jefferson JW, Johnson EM, Weiner ML. A reevaluation of risk of in utero exposure to lithium. JAMA. 1994 Jan 12;271(2):146-50.