Mass General Hospital

Harvard Medical School



Postpartum Depression: There’s An App For That

Researchers from the University of North Carolina’s School of Medicine and the Postpartum Depression: Action Towards Causes and Treatment Consortium have just released a free iPhone app which new mothers can use to diagnose postpartum depression. PPD ACTTM  surveys women to identify those who have had symptoms of PPD. The app also will invite certain women based […]

Continue Reading · 0
Credit: Pregnant Woman from Wikimedia Commons

Antidepressants and Postpartum Hemorrhage: No Risk with SSRIs, Small Risk with SNRIs

Serotonin reuptake inhibitor (SRI) antidepressants may affect platelet aggregation and thus may increase the risk of bleeding.  Several studies have sought to determine if exposure to SSRI antidepressants in late pregnancy is associated with an increased risk of postpartum hemorrhage. The most recent study was a population-based cohort study including 225,973 women with a total […]

Continue Reading · 0
Credit: Depressed Mother from Wikimedia Commons

Therapist-Assisted, Internet-Delivered CBT for Depression in Postpartum Women

  As we move toward universal screening for perinatal depression, one of our most significant challenges will be to evaluate and deliver care to the women who are identified as being depressed.  It is discouraging to note that recommendations regarding screening have not necessarily resulted in increased rates of treatment in women with perinatal depression. […]

Continue Reading · 0

Weekly Roundup for JULY 15 2016: Recent Publications in Women’s Mental Health

  This week a study published by Kieviet and colleagues gives us more information on the mechanism of poor neonatal adaptation in infants prenatally exposed to SSRIs and suggests that levels of maternal psychological distress modulate this risk.  Pugh and colleagues assessed the effectiveness of internet-delivered CBT for the management of perinatal depression. A Randomised […]

Continue Reading · 0
By Vera Kratochvil [Public domain], via Wikimedia Commons

More Data on SAGE-547, A Novel Treatment for Severe Postpartum Depression

About a year ago, we first reported on SAGE-547 (SAGE Therapeutics), a new medication for the treatment of severe postpartum depression.  SAGE-547  is a new drug, an allosteric modulator of GABAA receptors, which was initially under investigation for the treatment of refractory seizure disorders.  It turns out that SAGE-547 may also be useful for the […]

Continue Reading · 0

New Research from the CWMH: Evaluating the Risk of Major Malformations in Children Prenatally Exposed to Atypical Antipsychotics

Despite the increasing use of the newer “atypical” or second-generation antipsychotic agents to treat a spectrum of psychiatric disorders, including schizophrenia, bipolar disorder, major depression, PTSD and other anxiety disorders, we have relatively little data on the reproductive safety of these newer atypical agents. In response to this deficit, the National Pregnancy Registry for Atypical […]

Continue Reading · 0

Weekly Roundup for JULY 8 2016: Recent Publications in Women’s Mental Health

This week is pretty light.   Stress, the Placenta, and Fetal Programming of Behavior: Genes’ First Encounter With the Environment. Hoffman MC. Am J Psychiatry. 2016 Jul 1;173(7):655-7.  Distress During Pregnancy: Epigenetic Regulation of Placenta Glucocorticoid-Related Genes and Fetal Neurobehavior. Monk C, Feng T, Lee S, Krupska I, Champagne FA, Tycko B. Am J Psychiatry. […]

Continue Reading · 0
Baby Belly from Wikimedia Commons

Prenatal Cannabis Exposure May Affect Fetal Brain Development

With many states now moving forward with the legalization of medical marijuana, there seems to be a growing sense that marijuana is relatively safe and may, in some cases, be more attractive or effective than traditional medications for a spectrum of medical and psychiatric illnesses. The use of marijuana in the United States appears to […]

Continue Reading · 0

Weekly Roundup for JULY 1 2016: Recent Publications in Women’s Mental Health

Migration and perinatal mental health in women from low- and middle-income countries: a systematic review and meta-analysis.  Fellmeth G, Fazel M, Plugge E. BJOG. 2016 June 20. (Epub ahead of print) Early postnatal demoralisation among primiparous women in the community: measurement, prevalence and associated factors.  Bobevski I, Rowe H, Clarke DM, McKenzie DP, Fisher J. BMC […]

Continue Reading · 0