SSRIs, SNRIs, and Pregnancy: Reassuring Data on Neurodevelopmental Outcomes
A large meta-analysis finds no causal link between prenatal antidepressant exposure and neurodevelopmental disorders after accounting for confounding factors.
Rapid Symptom Relief in Postpartum Psychosis with Brexanolone
An open-label pilot study suggests that intravenous brexanolone may rapidly reduce psychotic, manic, and depressive symptoms in patients with postpartum psychosis, highlighting a potential new treatment option.
Clinical Update 2025: Recommendations on the Use of Antidepressants in Women Taking Tamoxifen
While some antidepressants may affect the metabolism of tamoxifen into its active form, many antidepressants can be used safely in this population.
Marlene Freeman, MD: Getting to the Truth About SSRIs and Pregnancy (Video)
The recent FDA expert panel focused largely on the risks of SSRIs during pregnancy; Dr. Freeman weighs in on the information provided in the report.
Information for Patients: How to Interpret the Recent FDA Panel on SSRIs and Pregnancy
The recent FDA expert panel focused largely on the risks of SSRIs during pregnancy but ignored or diminished the risks associated with untreated depression in the mother.Â
Weighing the Evidence: Response to the FDA’s Recent Panel on Antidepressant Use in Pregnancy.
The recent FDA expert panel focused largely on the risks of SSRIs during pregnancy but ignored or diminished the risks associated with untreated depression in the mother.Â
Essential Reads: Mirtazapine (Remeron) and Pregnancy
While we have adequate data to support the use of SSRI and SNRI antidepressants during pregnancy, there is less data regarding other classes of antidepressants. Although we less commonly use mirtazapine in pregnancy, several [...]
Yet Another Study: Antidepressants Do Not Increase Risk of Miscarriage
After accounting for maternal depression, there is little evidence of any association between antidepressant use during pregnancy and miscarriage.
Do SSRI Antidepressants Lower Risk of Preeclampsia? Maybe, But It’s Complicated
There is evidence that depression itself can increase risk for preeclampsia. In women with more severe depression, treatment with an SSRI antidepressant may decrease risk.
Neuroimaging Study Sheds Light on the Impact of Maternal Depression and Prenatal Antidepressant Exposure on Fetal Brain Development
At 7 years of age, children exposed to maternal depression during pregnancy or SSRI antidepressants exhibited similar changes in white matter architecture.