ABCL635 Shows Promise for Menopausal Hot Flashes in Phase 2 Trial
A new nonhormonal treatment targeting the neurokinin 3 receptor significantly reduced the frequency and severity of menopausal hot flashes in a Phase 2 trial.
ADHD Medications During Pregnancy: What Does the Latest Meta-Analysis Tell Us?
A new meta-analysis examines ADHD medication use during pregnancy, finding reassuring results for most outcomes while identifying a possible small increase in cardiovascular malformations with methylphenidate.
Essential Reads: Melatonin and Pregnancy (Clinical Update 2026)
Melatonin is widely used as a sleep aid, but what do we know about its safety during pregnancy? Explore the evidence, potential risks, and treatment options.
A Psychedelic Treatment for Postpartum Depression? Early Findings on GH001
A small phase 2a trial of GH001, an investigational psychedelic compound, found a rapid reduction in postpartum depression symptoms. Larger studies are needed to assess safety and durability.
Beyond Screening: Supporting the Mental Health of NICU Parents
Parents of infants in the NICU face high rates of depression, anxiety, stress, and trauma. Are we doing enough to identify their needs—and provide meaningful mental health support?
A Link Between Childhood Adversity and Polycystic Ovary Syndrome
In this North American cross-sectional study, higher exposure to early life adversities was associated with a higher lifetime prevalence of physician-diagnosed PCOS/PMOS. The findings add to growing evidence that childhood adversities may have lasting effects on reproductive health.
Beyond Reproductive Health: The Psychiatric Burden of Polyendocrine Metabolic Ovarian Syndrome (PMOS or PCOS)
Women with PMOS have significantly higher rates of depression and anxiety. Routine screening and integrated care are essential for improving psychiatric and reproductive outcomes.
Folic Acid Supplementation: When to Start? How Long to Continue?
Folic acid supplementation before and during early pregnancy substantially reduces the risk of neural tube defects. Emerging research suggests that folic acid may have beneficial effects on neurodevelopment that extend beyond the first trimester. We review the evidence on the timing of folic acid supplementation and findings from the FASSTT randomized controlled trial, which examined whether supplementation during the second and third trimesters was associated with improved cognitive outcomes in children.
Essential Reads: Why All Women of Reproductive Age Should Take Folic Acid
Folic Acid Awareness Week (Sept 13-19, 2026) focuses on the importance of daily folic acid supplements for women to prevent birth defects, as diet alone is often insufficient.
Quetiapine Use During Pregnancy: What Do We Know About Reproductive Safety?
For women who require treatment with quetiapine during pregnancy, the available reproductive safety data are generally reassuring. The largest body of evidence does not suggest a meaningful increase in major congenital malformations, while metabolic effects, particularly gestational diabetes, remain an important consideration.