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Archive | Menopausal Symptoms

Hormone Therapy May Prevent Depression in Perimenopausal Women: But What Are the Risks?

  Multiple studies have demonstrated that the menopausal transition is associated with a 2- to 4-fold increased risk for clinically significant depressive symptoms. There have been several studies suggesting that hormone therapy may improve depressive symptoms in women presenting with depression during this transition.  A recent study examined the efficacy of hormone replacement therapy in preventing […]

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Understanding the Interplay Between Depression and Menopausal Symptoms

  It has previously been reported that women seeking treatment at menopause clinics are more likely to report significant physical symptoms (e.g., vasomotor complaints), as well as depressive symptoms and anxiety. On the other hand, most women in the community do not experience significant depression while transitioning into the menopause. Thus, it is important to […]

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In Brief: Does Micronized Progesterone Relieve Perimenopausal Symptoms?

For decades, estrogen was used as a component of hormone replacement therapy to treat menopausal symptoms, including hot flashes, night sweats, and sleep disturbance; however, after several large, prospective studies (e.g., HERS, WHI) questioned the safety of long-term use of HRT, as well as its efficacy to prevent cardiovascular disease, many women have decided to […]

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Transdermal Estradiol, But Not Oral Estrogens, Improves Sexual Function in Postmenopausal Women

  Sexual dysfunction is common among peri- and postmenopausal women and include a spectrum of problems, including low (or hypoactive) sexual desire, decreased satisfaction, and discomfort.   Reports indicate that the prevalence of hypoactive sexual desire ranges from 9% in naturally postmenopausal women up to 26% in younger surgically postmenopausal women.  A recent study compares the […]

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In Brief: Night Sweats? Hot Flashes? Try Yoga

Yoga is frequently recommended as a treatment for menopause-related symptoms, including vasomotor symptoms and sleep disturbance; however, studies regarding its effectiveness have yielded mixed results. In a recent meta-anlsyis, researchers analyzed data from 13 randomized controlled trials with a total of 1306 participants. Compared with no treatment, yoga reduced total menopausal symptoms, and specifically led […]

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Psychiatric Clinics of North America: June Issue on Women’s Mental Health

In the field of reproductive psychiatry, we don’t really have any textbooks to rely on.  However, the June issue of the Psychiatric Clinics of North America is devoted to Women’s Mental Health, and it’s pretty much the most comprehensive guide on this topic. With articles from leaders in the field, it covers PMDD, medication use […]

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Neurokinin-3 Receptor Antagonists: A Novel Approach to the Treatment of Menopausal Symptoms

Over the last few years, we have seen a number of articles suggesting that the burden of menopausal symptoms is probably greater than generally perceived.  About 80% of women experience vasomotor symptoms (VMS) – hot flashes and night sweats — as they transition into the menopause.  For most, the symptoms are manageable, but for a […]

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In Brief:  Traumatic Events in Childhood and Adolescence Increase Risk for Perimenopausal Depression

  Previous studies have indicated that depression during the perimenopausal transition is associated with various risk factors, including previous history of depression, poor physical health, and more severe perimenopausal symptoms.  A recent study (reviewed here) indicates that women who experienced multiple traumatic events during childhood or adolescence are more likely to experience depression during the […]

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In Brief: Anxiety Associated with Worse Quality of Life in Postmenopausal Women

In a study including Latin American women 40 to 59 years of age who had not menstruated for more than 1 year (or had undergone a bilateral oophorectomy), 49.1% of the participants were depressed and 61.9% reported anxiety symptoms.  Although women with a history of psychiatric illness were excluded, rates of depression and anxiety observed […]

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Vasomotor Symptoms and the Importance of Maintaining a Healthy Body Weight

  While about 80% of peri- and postmenopausal women have vasomotor symptoms (VMS), such as night sweats and hot flashes, it has been observed that higher body mass index (BMI) and body fat are associated with an increased risk of vasomotor symptoms. Thus, it is reasonable to speculate that weight loss may prevent VMS. In […]

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