Depression

Perinatal Depression: How Do We Define High Risk? (Part 1)

In 2016, the US Preventive Services Task Force (USPSTF) recommended that all adults, including pregnant and postpartum women, should be screened for depression; the task force has extended those recommendations by stating that all pregnant [...]

Perinatal Depression and Anxiety: How Long Does It Last?

In the earliest studies, postpartum depression was described an episode of depression associated with childbirth, typically emerging within the first three months after delivery.  As more research has been carried out, we have learned that [...]

Predictors for New-Onset Severe Postpartum Psychiatric Disorders

A history of maternal psychiatric illness has been linked to postpartum depression (PPD), but this does not account for all instances of postpartum psychiatric illness. A recent study examined the impact of medical complications during [...]

Brexanolone: Related to Allopregnanolone, Effective for the Treatment of Postpartum Depression

In 2015, we first reported on SAGE-547 (SAGE Therapeutics), a new medication for the treatment of severe postpartum depression.  SAGE-547, now called brexanolone, is an allosteric modulator of GABAA receptors.  This drug was initially under [...]