Depression

Predictors for New-Onset Severe Postpartum Psychiatric Disorders

A history of maternal psychiatric illness has been linked to postpartum depression (PPD), but this does not account for all instances of postpartum psychiatric illness. A recent study examined the impact of medical complications during [...]

Brexanolone: Related to Allopregnanolone, Effective for the Treatment of Postpartum Depression

In 2015, we first reported on SAGE-547 (SAGE Therapeutics), a new medication for the treatment of severe postpartum depression.  SAGE-547, now called brexanolone, is an allosteric modulator of GABAA receptors.  This drug was initially under [...]

Prenatal SSRI Exposure and Speech/Language Disorders: Many Headlines, Little Risk

Last week, an article looking at the cognitive and motor development of children with prenatal exposure to antidepressants was published in JAMA Psychiatry.  Since that time, we have received a lot of questions regarding the [...]