More Data on Pregnancy Outcomes Associated with Lithium Use During Pregnancy
Lithium use during pregnancy was associated with an increased risk of preterm birth and large for gestational age infants.
Lithium use during pregnancy was associated with an increased risk of preterm birth and large for gestational age infants.
New findings from the National Pregnancy Registry for Atypical Antipsychotics provide reassuring data regarding the safety of prenatal exposure to lurasidone and quetiapine in a sample of well-characterized participants.
Based on this large cohort study including 990 pregnancies with first trimester exposure to atomoxetine, the researchers observed no increase in major congenital malformations overall and no statistically increased risk estimates for cardiac or limb malformations.
Although a small sample, no major malformations were observed in a prospectively followed cohort of women with first trimester exposure to buspirone.
Many women experience depression during pregnancy. What is the best way to identify these women?
These findings are encouraging and suggest that the newer AEDs, specifically lamotrigine and levetiracetam, are not associated with worse neurodevelopmental outcomes.
While questions and controversies remain, the information on long-term neurodevelopmental outcomes in children prenatally exposed to antidepressants is largely reassuring.
About 60% of women with mood disorders experience premenstrual exacerbation or PME of their mood during the premenstrual phase of their cycle.
The reality is that most of the antidepressants taken by women today are relatively safe and carry a very low risk to the developing fetus.
As soon as we published this article on the use of modafinil during pregnancy, another study was published which included data on the reproductive safety of modafinil and armodafinil from the US Provigil/Nuvigil Pregnancy [...]