Hormonal Therapy

Bioidentical, Compounded Hormones Commonly Used by Perimenopausal Women, But No Consistency

Increasing numbers of peri- and post-menopausal women request “bioidentical” rather than synthetic hormones.  Although there is a tendency to think of bioidentical hormones as “all-natural”, they, like synthetic hormones, are manufactured in the laboratory.  In [...]

In Brief: Hormone Therapy for Midlife Women, No Harm but No Benefit for Cognitive Functioning

Early observational studies suggested that hormone replacement therapy (HRT)  may improve cognitive functioning in postmenopausal women; however, larger studies, including the Women’s Health Initiative, have shown that estrogen replacement therapy started in postmenopausal women (65 [...]

Hormone Therapy May Prevent Depression in Perimenopausal Women: But What Are the Risks?

  Multiple studies have demonstrated that the menopausal transition is associated with a 2- to 4-fold increased risk for clinically significant depressive symptoms. There have been several studies suggesting that hormone therapy may improve depressive [...]

Estrogen Receptor Modulator Raloxifene for Women with Schizophrenia

Several years ago, we reviewed a paper suggesting that estrogen may have beneficial effects for women with schizophrenia.  In this study, women with schizophrenia were treated with estrogen in addition to their antipsychotic medications.  Adjunctive [...]

Hormone Replacement in Younger Menopausal Women: No Cognitive Benefit Detected

Early observational studies suggested that postmenopausal hormone treatment may improve cognitive functioning in women; however, studies from the Women’s Health Initiative have shown that estrogen replacement therapy started in postmenopausal women (65 years or older) [...]

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