Mass General Hospital

Harvard Medical School

Welcome to the MGH Center for Women’s Mental Health


Welcome to The Ammon-Pinizzotto Center for Women’s Mental Health at MGH. Our Center, established in 1989, has been renamed following the generous gift from Carol Ammon and Dr. Marie Pinizzotto. These resources will be used to realize the overarching mission of the Center.

This website provides a range of current information including discussion of new research findings in women’s mental health and how such investigations inform day-to-day clinical practice. Despite the growing number of studies being conducted in women’s health, the clinical implications of such work are frequently controversial, leaving patients with questions regarding the most appropriate path to follow. Providing these resources to patients and their doctors so that individual clinical decisions can be made in a thoughtful and collaborative fashion dovetails with the mission of our Center.

The National Pregnancy Registry for Psychiatric Medications:

All pregnant women ages 18-45 are eligible to enroll in the registry. The primary goal of this Registry is to determine the frequency of major malformations, such as heart defects, cleft lip, or neural tube defects, in infants exposed to atypical antipsychotics and antidepressants during pregnancy.  We are currently seeking both controls and those being treated with atypical antipsychotics and/ or antidepressants. For more information, please visit this page, call 1-866-961-2388 or e-mail


 EnBrace HR for MDD Relapse Prevention in         Women Trying to Conceive and Early Pregnancy:


Are you pregnant or planning a pregnancy? Do you feel depressed or have a history of depression? If you are less than 28 weeks pregnant or trying to conceive and have experienced depression now or in the past, you may be eligible to take part in a research study for the treatment of depression with a prenatal supplement. For more information, please visit this page, call Gina at 617-643-9284 or e-mail



Lifestyle Intervention Research Study Opportunity:

Are you pregnant or planning to become pregnant? Do you have a history of depression? Do you want to lose weight or have a healthier lifestyle? You may be eligible to participate in a research study at Massachusetts General Hospital evaluating a new lifestyle intervention for weight loss. Participants will receive 10 sessions of therapy at no cost to you.

If you are interested in participating or would like additional information, please call Samantha at 617-643-2076.


Recognition and Characterization of Obsessive-Compulsive Symptoms in Postpartum Women:

HAVE YOU HAD A BABY IN THE LAST 6 MONTHS? Take a minute to ask yourself the following questions.

  • Do you feel over-anxious all the time and not able to control it?
  • Are you having thoughts that you can’t get out of your mind or are you unable to concentrate, feeling like your mind goes blank?
  • Are you worried about a number of events and activities in particular about your baby?
  • Do you feel more nervous or irritable or your muscles are very tense?

If you recognize yourself in any of these questions, please help us research and characterize obsessive compulsive symptoms in postpartum women. Participation involves completing a survey that takes no more than 20 minutes:

For more information, if you have any questions or problems with this study please email the Principal Investigator (Dr. Baer) at


The MGH Center for Women’s Mental Health

Perinatal and Reproductive Psychiatry Program

Simches Research Building

185 Cambridge St Suite 2200

Boston, MA 02114


To make an appointment:

Massachusetts General Hospital Clinical Program: (617) 724-7792

Location of appointments: 

Wang Ambulatory Care Center, Massachusetts General Hospital

15 Parkman St., Floor 8

Boston, MA 02114-3117 

Latest News from our Blog

  • Weekly Roundup for FEBRUARY 17, 2017: Recent Publications in Women’s Mental Health

    February 17, 2017

      It was a light week, but a lot of articles on depression and anxiety in expectant and postpartum fathers.  Perinatal anxiety and depression are less common in men as compared to women but still a significant concern, especially because the father’s mental health issues may coincide with and exacerbate maternal depression and anxiety. Ruta Nonacs, MD ...

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  • Vasomotor Symptoms and the Importance of Maintaining a Healthy Body Weight

    February 16, 2017

    Photo by Christoph Lehmann

      While about 80% of peri- and postmenopausal women have vasomotor symptoms (VMS), such as night sweats and hot flashes, it has been observed that higher body mass index (BMI) and body fat are associated with an increased risk of vasomotor symptoms. Thus, it is reasonable to speculate that weight loss may prevent VMS. In a recent ...

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  • Postpartum Specific Anxiety Scale: A New Instrument for Assessing Postpartum Anxiety

    February 13, 2017

      Several studies suggest that postpartum anxiety is relatively common among postpartum women and may even be more common than depression.  Emerging evidence also suggests that a large number of postpartum women who do not meet diagnostic criteria for a specific anxiety disorder yet experience a clinically significant anxiety symptoms which are distinct from anxiety experienced ...

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  • Weekly Roundup for FEBRUARY 10, 2017: Recent Publications in Women’s Mental Health

    February 10, 2017

    The Neurobiology of Postpartum Anxiety and Depression. Pawluski JL, Lonstein JS, Fleming AS. Trends Neurosci. 2017 Feb;40(2):106-120. Functional Recovery After Postpartum Psychosis: A Prospective Longitudinal Study. Burgerhout KM, Kamperman AM, Roza SJ, Lambregtse-Van den Berg MP, Koorengevel KM, Hoogendijk WJ, Kushner SA, Bergink V.  J Clin Psychiatry. 2017 Jan;78(1):122-128. Implementation of Routine Postpartum Depression Screening and Care Initiation ...

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  • What Causes Poor Neonatal Adaptation in Antidepressant-Exposed Infants?

    February 8, 2017

    It was back in 2005 when we first reported on studies which demonstrated an increased risk of “poor neonatal adaptation” in infants with prenatal exposure to selective serotonin reuptake inhibitor (SSRI) antidepressants in late pregnancy.  Since that time, reports consistently indicate that about 25%-30% of infants exposed to SSRIs late in pregnancy manifest symptoms of ...

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  • How Can We Screen for Perinatal Depression in the Developing World?

    February 7, 2017

    While perinatal mood and anxiety disorders (PMAD) have a global footprint, the majority of research related to this group of illnesses has come largely from more affluent, Westernized countries.  Similarly, the tools used to detect and screen for PMADs were developed and tested in these Westernized countries.   The instrument most commonly used to detect PMADs ...

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