Mass General Hospital

Harvard Medical School

Welcome to the MGH Center for Women’s Mental Health


Welcome to The Ammon-Pinizzotto Center for Women’s Mental Health at MGH. Our Center, established in 1989, has been renamed following the generous gift from Carol Ammon and Dr. Marie Pinizzotto. These resources will be used to realize the overarching mission of the Center.

This website provides a range of current information including discussion of new research findings in women’s mental health and how such investigations inform day-to-day clinical practice. Despite the growing number of studies being conducted in women’s health, the clinical implications of such work are frequently controversial, leaving patients with questions regarding the most appropriate path to follow. Providing these resources to patients and their doctors so that individual clinical decisions can be made in a thoughtful and collaborative fashion dovetails with the mission of our Center.

The National Pregnancy Registry for Psychiatric Medications:

All pregnant women ages 18-45 are eligible to enroll in the registry. We are currently seeking both controls and those being treated with atypical antipsychotics and/ or antidepressants.

This study will involve 3 brief phone interviews over an 8-month period. The National Pregnancy Registry for Psychiatric Medications is dedicated to evaluating the safety of psychiatric medications that may be taken by women during pregnancy to treat a wide range of mood, anxiety, or psychiatric disorders. The primary goal of this Registry is to determine the frequency of major malformations, such as heart defects, cleft lip, or neural tube defects, in infants exposed to atypical antipsychotics and antidepressants during pregnancy. For more information, please call 1-866-961-2388 or e-mail

Help make the future better for many other women like you.

The MGH Center for Women’s Mental Health

Perinatal and Reproductive Psychiatry Program

Simches Research Building

185 Cambridge St Suite 2200

Boston, MA 02114


To make an appointment:

Massachusetts General Hospital Clinical Program: (617) 724-7792

Location of appointments: 

Wang Ambulatory Care Center, Massachusetts General Hospital

15 Parkman St., Floor 8

Boston, MA 02114-3117 

Latest News from our Blog

  • SSRIs and Pregnancy: No Risk of Cardiovascular Malformations According to UK Study

    May 24, 2016

    Baby Belly from Wikimedia Commons

    Over the last few years, several studies have suggested an increased risk of certain types of cardiovascular malformations in children exposed to selective serotonin reuptake inhibitors (SSRIs) during pregnancy. The first reports suggested a link between cardiac septal defects and exposure to paroxetine; other, but not all, studies have also shown an elevated risk of ...

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  • Positive Parental Engagement Protects Children from the Detrimental Effects of Prenatal Stress

    May 23, 2016

    Credit: Pregnant Woman from Wikimedia Commons

      Studies in animals and humans suggest that psychological distress experienced by mothers during pregnancy is associated with later neurodevelopmental problems in their offspring.  Project Ice Storm is one such study exploring the effect of prenatal maternal stress on child cognitive functioning. In January 1998, an  ice storm hit the Canadian province of Quebec and resulted in ...

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  • Weekly Roundup for MAY 20 2016: Publications in Reproductive Psychiatry

    May 20, 2016


    Selective serotonin reuptake inhibitors and congenital heart anomalies:comparative cohort studies of women treated before and during pregnancy and their children. Petersen I, Evans SJ, Gilbert R, Marston L, Nazareth I. J Clin Psychiatry. 2016 Jan;77(1):e36-42. Factors influencing attempted and completed suicide in postnatal women: A population-based study in Taiwan. Weng SC, Chang JC, Yeh MK, Wang SM, Chen YH. Sci ...

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  • Maternal Depression and Its Effects on the Child:  What is the Role of Oxytocin?

    May 19, 2016

    By Vera Kratochvil [Public domain], via Wikimedia Commons

    There is significant literature indicating that a mother’s depression may adversely affect her young child.  Studies have demonstrated that the children of depressed mothers are more likely than the children of non-depressed mothers to exhibit developmental delays and childhood behavioral problems.  It has also been demonstrated that the children of depressed mothers are more likely ...

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  • Pregnancy Brain? Or a Symptom of Depression?

    May 17, 2016


    During pregnancy, many women complain that they feel more distractible, more forgetful or less sharp than before pregnancy. A few years ago, we reviewed a study which demonstrated that performance on tests of spatial recognition memory (SRM) were adversely affected by pregnancy. Other aspects of executive function were unaffected.   A recent study assessed working memory ...

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  • Suicide Rates Increasing in Women, Adolescent Girls

    May 16, 2016


    According to a recent report from the Centers for Disease Control and Prevention, suicide rates in the United States are on the rise, especially in women.  From 1999 through 2014, the age-adjusted suicide rate in the United States increased 24%, from 10.5 to 13.0 per 100,000 population.  The suicide rate increased by 1% yearly between ...

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