Mass General Hospital

Harvard Medical School

Welcome to the MGH Center for Women’s Mental Health


Welcome to The Ammon-Pinizzotto Center for Women’s Mental Health at MGH. Our Center, established in 1989, has been renamed following the generous gift from Carol Ammon and Dr. Marie Pinizzotto. These resources will be used to realize the overarching mission of the Center.

This website provides a range of current information including discussion of new research findings in women’s mental health and how such investigations inform day-to-day clinical practice. Despite the growing number of studies being conducted in women’s health, the clinical implications of such work are frequently controversial, leaving patients with questions regarding the most appropriate path to follow. Providing these resources to patients and their doctors so that individual clinical decisions can be made in a thoughtful and collaborative fashion dovetails with the mission of our Center.

The National Pregnancy Registry for Psychiatric Medications:

All pregnant women ages 18-45 are eligible to enroll in the registry. The primary goal of this Registry is to determine the frequency of major malformations, such as heart defects, cleft lip, or neural tube defects, in infants exposed to atypical antipsychotics and antidepressants during pregnancy.  We are currently seeking both controls and those being treated with atypical antipsychotics and/ or antidepressants. For more information, please visit this page, call 1-866-961-2388 or e-mail


 EnBrace HR for MDD Relapse Prevention in         Women Trying to Conceive and Early Pregnancy:


Are you pregnant or planning a pregnancy? Do you feel depressed or have a history of depression? If you are less than 28 weeks pregnant or trying to conceive and have experienced depression now or in the past, you may be eligible to take part in a research study for the treatment of depression with a prenatal supplement. For more information, please visit this page, call Gina at 617-643-9284 or e-mail



Lifestyle Intervention Research Study Opportunity:

Are you pregnant or planning to become pregnant? Do you have a history of depression? Do you want to lose weight or have a healthier lifestyle? You may be eligible to participate in a research study at Massachusetts General Hospital evaluating a new lifestyle intervention for weight loss. Participants will receive 10 sessions of therapy at no cost to you.

If you are interested in participating or would like additional information, please call Samantha at 617-643-2076.


Recognition and Characterization of Obsessive-Compulsive Symptoms in Postpartum Women:

HAVE YOU HAD A BABY IN THE LAST 6 MONTHS? Take a minute to ask yourself the following questions.

  • Do you feel over-anxious all the time and not able to control it?
  • Are you having thoughts that you can’t get out of your mind or are you unable to concentrate, feeling like your mind goes blank?
  • Are you worried about a number of events and activities in particular about your baby?
  • Do you feel more nervous or irritable or your muscles are very tense?

If you recognize yourself in any of these questions, please help us research and characterize obsessive compulsive symptoms in postpartum women. Participation involves completing a survey that takes no more than 20 minutes:

For more information, if you have any questions or problems with this study please email the Principal Investigator (Dr. Baer) at


The MGH Center for Women’s Mental Health

Perinatal and Reproductive Psychiatry Program

Simches Research Building

185 Cambridge St Suite 2200

Boston, MA 02114


To make an appointment:

Massachusetts General Hospital Clinical Program: (617) 724-7792

Location of appointments: 

Wang Ambulatory Care Center, Massachusetts General Hospital

15 Parkman St., Floor 8

Boston, MA 02114-3117 

Latest News from our Blog

  • Dietary Supplements to Prevent Postpartum Depression? Proceed with Caution

    March 21, 2017

    Over the last few days, there has been a lot of buzz regarding the use of a nutritional supplement to reduce risk of postpartum depression.  Quoting one of these articles:  “‘Women who take the supplement don’t get sad ,’ said Dr. Jeffrey Meyer, co-author of a study testing this blues-banishing ...

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  • Stimulants In Pregnancy and Increased Risk of Gestational Hypertension

    March 20, 2017

      Our group has noted that we are seeing an increase in the number of consultations for women treated with psychostimulants in combination with an antidepressant.  The reasons vary.  Some women have depression and comorbid attention-deficit/hyperactivity disorder (ADHD).  Sometimes a psychostimulant is used to manage residual symptoms and side effects, such as fatigue and cognitive deficits. ...

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  • Weekly Roundup for MARCH 17, 2017: Recent Publications in Women’s Mental Health

    March 17, 2017

      The most interesting article this week is from Dowlati and colleagues assessing the effectiveness of a nutritional supplement to decrease risk for postpartum blues.  While intriguing, it is not clear how effective this intervention will prove to be.   We will have a post on this paper next week.     Dowlati Y, Ravindran AV, Segal ZV, Stewart ...

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  • Synthetic Oxytocin and Its Effect on Postpartum Mood and Anxiety

    March 15, 2017

    Often referred to as the “hormone of love,” oxytocin plays an important role in childbirth, maternal behavior, lactation, social affiliation, and sexual pleasure.  Levels of oxytocin, a neuropeptide produced by the hypothalamus and released into the bloodstream via the pituitary gland, rise around the time of delivery.   These levels remain high after delivery, specifically increasing ...

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  • Effectiveness of Psychological Interventions for Postpartum Depression in Primary Care

    March 13, 2017

      Postpartum depression (PPD) has been identified as the “most under-recognized, under-diagnosed, and under-treated obstetrical complication in America”, affecting approximately 10-15% of new mothers. In addition to affecting maternal mental health during a critical time in a woman’s life, there are are a number of downstream effects associated with undiagnosed or untreated PPD such as impaired ...

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  • Postpartum Progress: An Update and Other Resources

    March 10, 2017

    We were saddened to hear that Postpartum Progress, Inc. is in the process of shutting down.  Since its inception in 2004, Postpartum Progress has been an important resource for women with perinatal mood and anxiety disorders.  This organization — and all of the women behind it — have made such vital contributions in terms of ...

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