Mass General Hospital

Harvard Medical School

Welcome to the MGH Center for Women’s Mental Health


Welcome to The Ammon-Pinizzotto Center for Women’s Mental Health at MGH. Our Center, established in 1989, has been renamed following the generous gift from Carol Ammon and Dr. Marie Pinizzotto. These resources will be used to realize the overarching mission of the Center.

This website provides a range of current information including discussion of new research findings in women’s mental health and how such investigations inform day-to-day clinical practice. Despite the growing number of studies being conducted in women’s health, the clinical implications of such work are frequently controversial, leaving patients with questions regarding the most appropriate path to follow. Providing these resources to patients and their doctors so that individual clinical decisions can be made in a thoughtful and collaborative fashion dovetails with the mission of our Center.

The National Pregnancy Registry for Psychiatric Medications:

All pregnant women ages 18-45 are eligible to enroll in the registry. We are currently seeking both controls and those being treated with atypical antipsychotics and/ or antidepressants.

This study will involve 3 brief phone interviews over an 8-month period. The National Pregnancy Registry for Psychiatric Medications is dedicated to evaluating the safety of psychiatric medications that may be taken by women during pregnancy to treat a wide range of mood, anxiety, or psychiatric disorders. The primary goal of this Registry is to determine the frequency of major malformations, such as heart defects, cleft lip, or neural tube defects, in infants exposed to atypical antipsychotics and antidepressants during pregnancy. For more information, please call 1-866-961-2388 or e-mail

Help make the future better for many other women like you.

The MGH Center for Women’s Mental Health

Perinatal and Reproductive Psychiatry Program

Simches Research Building

185 Cambridge St Suite 2200

Boston, MA 02114


To make an appointment:

Massachusetts General Hospital Clinical Program: (617) 724-7792

Location of appointments: 

Wang Ambulatory Care Center, Massachusetts General Hospital

15 Parkman St., Floor 8

Boston, MA 02114-3117 

Latest News from our Blog

  • The Pediatric Emergency Department: Another Opportunity for Postpartum Screening

    May 1, 2016

    Credit: Depressed Mother from Wikimedia Commons

    Earlier this year, the U.S. Preventive Services Task Force (USPSTF) released recommendations on Screening for Depression in Adults. The Task Force recommends that clinicians screen ALL ADULTS for depression and notes that the evidence indicates that screening in the primary care setting is beneficial. Echoing the recommendations made by the American College of Obstetricians and ...

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  • Premenstrual Mood Disorders and Postpartum Depression: Similar But Different

    April 28, 2016


    It has been hypothesized that both premenstrual dysphoric disorder (PMDD) and postpartum depression (PPD) occur as the result of rapid shifts in the levels of ovarian hormones. Data regarding the prevalence of PPD among women with documented PPD is sparse, and the existent studies rely upon recall of premenstrual symptoms which is notoriously inaccurate.  Despite ...

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  • What Are the Long Term Effects of Prenatal Antidepressant Exposure?

    April 27, 2016

    Baby Belly from Wikimedia Commons

    At this point in time, we have considerable information regarding the reproductive safety of antidepressants, particularly the selective serotonin reuptake inhibitors or SSRIs.  Most of this information relates to the incidence of congenital malformations or birth defects in children exposed to these medications.  Other studies have examined the effects of the medications on newborn adaptation ...

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  • HEART: An Innovative Program for Identifying and Treating Adolescent Mothers with Depression

    April 18, 2016


    Multiple studies have shown that routine medical care is not adequate when it comes to identifying and treating women with perinatal mood disorders.  Universal screening can help to increase the identification of mothers with mood and anxiety disorders during pregnancy and the postpartum period; however, there are still significant obstacles in terms of accessing mental ...

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  • Lamotrigine and Pregnancy: New Study, No Significant Increase in Risk of Oral Clefts

    April 11, 2016

    baby ultrasound

    The anticonvulsant lamotrigine (Lamictal) is being used with increasing regularity for the treatment of women with bipolar disorder.  Back in 2006, we reported on preliminary data indicating an increased risk of oral clefts among infants exposed to lamotrigine during the first trimester of pregnancy.  It has been a while since we reviewed the data regarding ...

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  • Teen Mothers: How Can We Best Address Their Mental Health Needs?

    April 8, 2016


      The Good News:  According to the CDC, rates of teen pregnancy are falling  In the United States, 249,078 babies were born to women aged 15–19 years in 2014.  This represents a historic low for births among U.S. teens, a drop of 9% from 2013. The Bad News:   Pregnant teens — especially when they don’t have the ...

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