Mass General Hospital

Harvard Medical School

Welcome to the MGH Center for Women’s Mental Health


Welcome to The Ammon-Pinizzotto Center for Women’s Mental Health at MGH. Our Center, established in 1989, has been renamed following the generous gift from Carol Ammon and Dr. Marie Pinizzotto. These resources will be used to realize the overarching mission of the Center.

This website provides a range of current information including discussion of new research findings in women’s mental health and how such investigations inform day-to-day clinical practice. Despite the growing number of studies being conducted in women’s health, the clinical implications of such work are frequently controversial, leaving patients with questions regarding the most appropriate path to follow. Providing these resources to patients and their doctors so that individual clinical decisions can be made in a thoughtful and collaborative fashion dovetails with the mission of our Center.

The National Pregnancy Registry for Psychiatric Medications:

All pregnant women between the ages of 18-45 with a history of psychiatric illness are eligible to enroll in the registry. The primary goal of this Registry is to determine the frequency of major malformations, such as heart defects, cleft lip, or neural tube defects, in infants exposed to atypical antipsychotics and antidepressants during pregnancy.  We are currently seeking both controls and those being treated with atypical antipsychotics and/ or antidepressants. For more information, please visit this page, call 1-866-961-2388 or e-mail

Course of ADHD in Pregnancy and the Postpartum

Are you pregnant? Do you have a history of ADHD?

If you are less than 20 weeks pregnant and have a history of ADHD, you may be eligible to take part in an observational research study for women maintaining, decreasing, or discontinuing psychostimulants during pregnancy and the postpartum. Women who participate will have 6 study visits from time of enrollment (<20 weeks pregnant) to 24 weeks postpartum.  The first visit must be in-person at Massachusetts General Hospital with the option to complete the remaining visits in-person or over the phone.

For more information, please call (617)726-2912 or email the study coordinator at



 EnBrace HR for MDD Relapse Prevention in         Women Trying to Conceive and Early Pregnancy:


Are you pregnant or planning a pregnancy? Do you feel depressed or have a history of depression? If you are less than 28 weeks pregnant or trying to conceive and have experienced depression now or in the past, you may be eligible to take part in a research study for the treatment of depression with a prenatal supplement. For more information, please visit this page, call Taylor at 617-643-9284 or email



Lifestyle Intervention Research Study Opportunity:

Are you pregnant or planning to become pregnant? Do you have a history of depression? Do you want to lose weight or have a healthier lifestyle? You may be eligible to participate in a research study evaluating a new lifestyle intervention for weight loss. Participants will receive 10 sessions of therapy at no cost to you.

If you are interested in participating or would like additional information, please call Samantha at 617-643-2076.


The MGH Center for Women’s Mental Health

Perinatal and Reproductive Psychiatry Program

Simches Research Building

185 Cambridge St Suite 2200

Boston, MA 02114


To make an appointment:

Massachusetts General Hospital Clinical Program: (617) 724-7792

Location of appointments: 

Wang Ambulatory Care Center, Massachusetts General Hospital

15 Parkman St., Floor 8

Boston, MA 02114-3117 

Latest News from our Blog

  • Managing Opioid Dependence in Pregnancy: Outcomes in Children Exposed to Buprenorphine, Naltrexone, or Methadone

    December 7, 2017

    The use of opioid drugs in women of childbearing age has become a pressing public health concern.  It is clear that opiate use during pregnancy puts the mother and child at risk; opiate use during pregnancy has been associated with increased risk for oral clefts, neural tube defects, congenital heart defects, and ophthalmic problems.  In ...

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  • Weekly Roundup for December 1, 2017: Recent Publications in Women’s Mental Health

    December 1, 2017

    Postpartum Depression Screening Tools: A Review. Psychosomatics 2017. No tool could be deemed best at accurately detecting PPD on the basis of sensitivity and specificity. Additionally, there was no recommended time period in which screening should be done. It Is Time for Routine Screening for Perinatal Mood and Anxiety Disorders in Obstetrics and Gynecology Settings. Accortt EE, Wong ...

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  • Higher Prepregnancy BMI Linked to Higher Rates of Maternal Morbidity

    November 28, 2017

      In the United States, about half of all pregnant women are overweight or obese. A recent study indicates that higher prepregnancy body mass index (BMI) is associated with a higher risk of maternal morbidity.  In this study carried out in Washington State, 743,630 women were included. Prepregnancy BMI was distributed as follows: underweight, 3.2%; normal weight, ...

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  • Weekly Roundup for November 24, 2017: Recent Publications in Women’s Mental Health

    November 24, 2017

      This week there are some very interesting articles looking at the effects of negative childhood experiences on risk for postpartum depression and impaired mother-infant bonding.  In a large population-based study, Meltzer-Brody and colleagues reported that adverse life events experienced during childhood, primarily the result of to parental psychopathology, are at increased risk of postpartum psychiatric ...

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  • Depression in Fathers Increases Risk for Adolescent Depression

    November 21, 2017

    According to a study published last year in the journal Pediatrics, adolescent depression is on the rise. In adolescents, the 12-month prevalence of major depression increased from 8.7% in 2005 to 11.3% in 2014.  Other studies have noted an increase in rates of suicide among adolescents, particularly girls; among girls aged 10-14, the suicide rate ...

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  • Weekly Roundup for November 17, 2017: Recent Publications in Women’s Mental Health

    November 17, 2017

    The article that received the most attention this week is one examining the risks associated with the use of stimulants to treat ADHD during pregnancy (Cohen JM et al, 2017).  There were no real surprises here, but the study suffers from many of the same shortcomings as other studies investigating the effects of other psychotropic ...

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