Mass General Hospital

Harvard Medical School

Welcome to the MGH Center for Women’s Mental Health


Welcome to The Ammon-Pinizzotto Center for Women’s Mental Health at MGH. Our Center, established in 1989, has been renamed following the generous gift from Carol Ammon and Dr. Marie Pinizzotto. These resources will be used to realize the overarching mission of the Center.

This website provides a range of current information including discussion of new research findings in women’s mental health and how such investigations inform day-to-day clinical practice. Despite the growing number of studies being conducted in women’s health, the clinical implications of such work are frequently controversial, leaving patients with questions regarding the most appropriate path to follow. Providing these resources to patients and their doctors so that individual clinical decisions can be made in a thoughtful and collaborative fashion dovetails with the mission of our Center.

The National Pregnancy Registry for Psychiatric Medications:

All pregnant women ages 18-45 are eligible to enroll in the registry. The primary goal of this Registry is to determine the frequency of major malformations, such as heart defects, cleft lip, or neural tube defects, in infants exposed to atypical antipsychotics and antidepressants during pregnancy.  We are currently seeking both controls and those being treated with atypical antipsychotics and/ or antidepressants. For more information, please visit this page, call 1-866-961-2388 or e-mail


 EnBrace HR for MDD Relapse Prevention in         Women Trying to Conceive and Early Pregnancy:

  Are you pregnant or planning pregnancy? If you have a history of depression and have decided to discontinue antidepressants for pregnancy, you may be eligible to take part in a research study for the treatment of depression with a prenatal supplement. For more information, please visit this page, call Gina at 617-643-9284 or e-mail



Recognition and Characterization of Obsessive-Compulsive Symptoms in Postpartum Women:

HAVE YOU HAD A BABY IN THE LAST 6 MONTHS? Take a minute to ask yourself the following questions.

  • Do you feel over-anxious all the time and not able to control it?
  • Are you having thoughts that you can’t get out of your mind or are you unable to concentrate, feeling like your mind goes blank?
  • Are you worried about a number of events and activities in particular about your baby?
  • Do you feel more nervous or irritable or your muscles are very tense?

If you recognize yourself in any of these questions, please help us research and characterize obsessive compulsive symptoms in postpartum women. Participation involves completing a survey that takes no more than 20 minutes:

For more information, if you have any questions or problems with this study please email the Principal Investigator (Dr. Baer) at


The MGH Center for Women’s Mental Health

Perinatal and Reproductive Psychiatry Program

Simches Research Building

185 Cambridge St Suite 2200

Boston, MA 02114


To make an appointment:

Massachusetts General Hospital Clinical Program: (617) 724-7792

Location of appointments: 

Wang Ambulatory Care Center, Massachusetts General Hospital

15 Parkman St., Floor 8

Boston, MA 02114-3117 

Latest News from our Blog

  • Weekly Roundup for JANUARY 20, 2017: Recent Publications in Women’s Mental Health

    January 20, 2017

    Happy New Year!  We are not even three weeks into January, and it promises to be a busy year.  At the top of the list is the study from Cantarutti and colleagues which observed that depression in itself, rather than antidepressant medication, might increase risk for preterm birth and low birth weight. There are also several ...

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  • Is BDNF a Biomarker for Depression During Pregnancy and the Postpartum Period?

    January 19, 2017

    Brain-derived neurotrophic factor (BDNF) is a growth factor which acts on neurons in both the central and peripheral nervous systems, promoting the survival of neurons and promoting the growth and differentiation of new neurons and synapses.  In the brain, it is most active in the hippocampus, cortex, and basal forebrain—areas important  to learning, memory, and ...

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  • Pregnancy Termination Does Not Affect Women’s Long-term Mental Health or Well-Being

    January 12, 2017

    The US Surgeon General made the recommendation in 1989 that a five-year longitudinal cohort study was necessary to provide data about the health effects of an elective termination on women. To rise to this challenge, the Turnaway Study was launched at the University of California, San Francisco Bixby Center for Global Reproductive Health. This prospective, ...

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  • Postpartum Depression in Women with No History of Psychiatric Illness

    January 10, 2017

    Most studies observe that about 15% of women experience postpartum depression (PPD).  For the majority of women who present with postpartum depression, the postpartum episode is not the first ever episode of depression and instead represents a recurrence.  These women report a pattern of recurrent depressive illness consisting of both puerperal and nonpuerperal episodes.   But ...

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  • USPSTF Emphasizes Periconceptual Use of Folic Acid to Prevent Birth Defects

    January 10, 2017

    Neural tube defects are among the most common major congenital anomalies in the United States and are associated with significant disability and death.  The risk of neural tube defects can be prevented with daily folic acid supplementation in the periconceptional period.  However, most women do not receive the recommended daily intake of folate.  January 5–11 ...

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  • Goodbye 2016: The Year in Review

    January 6, 2017

    Happy New Year! It is that time of the year again when we take the time to look back and review the previous year.  Probably the most striking thing I see is the sheer volume of articles published in the field of reproductive psychiatry.   This means that it has been a great year for our website ...

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