Based on this large cohort study including 990 pregnancies with first trimester exposure to atomoxetine, the researchers observed no increase in major congenital malformations overall and no statistically increased risk estimates for cardiac or limb malformations.
There is evidence that depression itself can increase risk for hypertension and preeclampsia. Future studies will help to clarify the complex interaction between depression, SSRI treatment and pre-eclampsia.
Prenatal exposure to valproic acid was associated with an increased risk of autism spectrum disorder in exposed children.
Essential Reads: Modafinil and Armodafinil During Pregnancy Associated with Increased Risk of Malformations
Modafinil (brand name Provigil) and armodafinil (Nuvigil) are wake-promoting agents used to treat sleepiness due to narcolepsy, shift work sleep disorder, or obstructive sleep apnea. They are also used in other settings, often in [...]
Prenatal exposure to valproate has been associated with an elevated risk (10%) for a broad range of congenital malformations including neural tube defects, as well as adverse neurodevelopmental sequelae, including lower IQ and developmental delays [...]
While we have considerable information regarding the teratogenic risk associated with prenatal exposure to various antiepileptic drugs (AEDs), we have considerably less information on the impact of exposure to AEDs on behavioral outcomes in [...]
Clinical Update 2020: Lamotrigine (Lamictal) and Pregnancy Maintenance treatment with a mood stabilizer during pregnancy can significantly reduce the risk of relapse in women with bipolar disorder; however, many of the mood stabilizers commonly [...]
Maternal Anxiety and Adverse Perinatal Outcomes: Why We Need to Screen Women for Anxiety During Pregnancy
When providing information to patients regarding the use of medications during pregnancy, one key element of the decision-making process is an appraisal of the risks associated with untreated psychiatric illness in the mother. While there [...]
For women with bipolar disorder, choosing whether to maintain or discontinue treatment with a mood stabilizer during pregnancy is challenging. This is a process which requires careful and thoughtful consideration, weighing the risk of adverse [...]
According to a recent analysis of national data by the Centers for Disease Control, the number of pregnant women with opioid use disorder (as documented at the time of delivery) more than quadrupled from 1999 [...]