• Pregnancy Outcomes

    Essential Reads: Modafinil and Armodafinil During Pregnancy Associated with Increased Risk of Malformations

    Modafinil (brand name Provigil) and armodafinil (Nuvigil) are wake-promoting agents used to treat sleepiness due to narcolepsy, shift work sleep disorder, or obstructive sleep apnea. They are also used in other settings, often in [...]

    Is it Safe to Use Atomoxetine (Strattera) During Pregnancy?

    Based on this large cohort study including 990 pregnancies with first trimester exposure to atomoxetine, the researchers observed no increase in major congenital malformations overall and no statistically increased risk estimates for cardiac or limb malformations.

    Prenatal Valproic Acid (Depakote) Exposure Increases Risk for Neurodevelopmental Disorders

    While we have considerable information regarding the teratogenic risk associated with prenatal exposure to various antiepileptic drugs (AEDs), we have considerably less information on the impact of exposure to AEDs on behavioral outcomes in [...]

    Maternal Anxiety and Adverse Perinatal Outcomes: Why We Need to Screen Women for Anxiety During Pregnancy

    When providing information to patients regarding the use of medications during pregnancy, one key element of the decision-making process is an appraisal of the risks associated with untreated psychiatric illness in the mother.  While there [...]

    Lithium and Anticonvulsant Mood Stabilizers: No Higher Risk for Adverse Pregnancy Outcomes

    For women with bipolar disorder, choosing whether to maintain or discontinue treatment with a mood stabilizer during pregnancy is challenging.  This is a process which requires careful and thoughtful consideration, weighing the risk of adverse [...]

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