Psychiatric Disorders During Pregnancy

Essential Reads: Should Lithium Dose Be Reduced Prior to Delivery?

The dosing of lithium presents certain challenges during pregnancy.  During pregnancy, there is a physiologic increase in the glomerular filtration rate (GFR), which is a measure of how quickly the kidney clears renally excreted compounds, [...]

New Research from the CWMH: No Increase in Major Malformations in Children Prenatally Exposed to Aripiprazole

Despite the increasing use of the newer atypical or second-generation antipsychotic agents to treat a spectrum of psychiatric disorders, including psychotic disorders, bipolar disorder, major depression, PTSD and other anxiety disorders, we have relatively little [...]

Prescription Opioids During Pregnancy and Risk for Major Malformations

Previous studies have suggested a link between opioid exposure during pregnancy and increased risk of certain major malformations, including neural tube defects.  A recent study from Bateman and colleagues assesses the risk of major malformation [...]

Exploring the Link Between Prenatal Adversity and Adolescent Psychiatric Risk

We have long been concerned about the impact of prenatal stress on fetal development and subsequent risk for developmental problems and psychiatric morbidity.  Various studies have demonstrated an association between maternal depression and anxiety during [...]

Probiotics for Prenatal Depression and Anxiety: Underscoring the Need for More Research

Although we have data on the reproductive safety of various medications used to treat anxiety, many women would understandably prefer to avoid medications when possible.  Many women ask about alternative treatments, including dietary supplements, herbal [...]

Prenatal Exposure to Valproic Acid Linked to Increased Risk for Autism, ADHD

Prenatal exposure to valproate has been associated with an elevated risk (10%) for a broad range of congenital malformations including neural tube defects, as well as adverse neurodevelopmental sequelae, including lower IQ and developmental delays [...]

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