• Bipolar Disorder

    Maternal Bipolar Disorder Not a Predictor of Infant Developmental Deficits at One Year of Age

      While some women with bipolar disorder elect to discontinue their psychotropic medications during pregnancy to mitigate fetal exposure, Viguera and colleagues (2000, 2007) found that women stabilized on lithium face a significant risk for [...]

    Lamotrigine and Pregnancy: Meta-Analysis Shows No Increase in Risk for Malformations

      Maintenance treatment with a mood stabilizer during pregnancy can significantly reduce the risk of relapse in women with bipolar disorder; however, many of the mood stabilizers commonly used in this setting, including lithium and [...]

    Screening for Depression During Pregnancy May Lead to Misdiagnosis for Women with Bipolar Disorder

    The American College of Obstetrics and Gynecology now recommends that women be screened for depression during pregnancy.  Because depressive symptoms during pregnancy have been associated with worse outcomes and are a robust predictor of postpartum [...]

    Postpartum Psychosis Can be Prevented in Women at High Risk

    It is well-established that women with a history of bipolar disorder or postpartum psychosis are at extremely high risk of postpartum psychiatric illness. Several studies have indicated that lithium prophylaxis can dramatically reduce the risk of postpartum relapse; however, the studies have varied in terms of the timing of prophylaxis, with some initiating treatment during pregnancy and others initiating treatment immediately after delivery.  A recent study published in the American Journal of Psychiatry gives more information on the clinical management of these high risk populations.

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