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Tag Archives | postpartum depression

In Brief: Problem-Solving Education Intervention Reduces Risk of Postpartum Depression

  While many women are at risk for postpartum depression, we continue to struggle in providing adequate support and care to women in this setting, especially socioeconomically disadvantaged women.   In a randomized clinical trial including 230 Head Start mothers, those receiving problem-solving education (PSE) were 60% less likely to develop postpartum depression than those […]

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Pilot Study of Telephone-Delivered Interpersonal Therapy for Women with Postpartum Depression

It is clear that screening for perinatal depression substantially improves detection; however, screening alone does not appear to improve rates of treatment or outcomes.  What we find is that many, if not most, women with perinatal depression do not receive adequate care.  There appear to be many obstacles: stigma associated with mental illness, lack of […]

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Brexanolone: Related to Allopregnanolone, Effective for the Treatment of Postpartum Depression

In 2015, we first reported on SAGE-547 (SAGE Therapeutics), a new medication for the treatment of severe postpartum depression.  SAGE-547, now called brexanolone, is an allosteric modulator of GABAA receptors.  This drug was initially under investigation for the treatment of refractory seizure disorders but it turned out to be a good antidepressant.  The information we […]

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Perinatal Depression in Fathers: Who is At Greatest Risk?

While perinatal depression is typically considered to be a woman’s illness, a number of studies have suggested that, although men do not experience any of the dramatic physiologic or hormonal changes that go along with pregnancy and the postpartum period, new fathers may also experience perinatal depression. In a cohort study of 3523 new fathers […]

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Perinatal Depression Screening Is Just The Start

The following post was first published in OB/GYN News. Please see our OB/GYN News archives here. Publish date:  March 3, 2017 Over the last decade, appreciation of the prevalence of perinatal depression – depression during pregnancy and/or the postpartum period – along with interest and willingness to diagnose and to treat these disorders across primary care, obstetric, […]

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Dietary Supplements to Prevent Postpartum Depression? Proceed with Caution

Over the last few days, there has been a lot of buzz regarding the use of a nutritional supplement to reduce risk of postpartum depression.  Quoting one of these articles:  “‘Women who take the supplement don’t get sad [in the early days of motherhood],’ said Dr. Jeffrey Meyer, co-author of a study testing this blues-banishing […]

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Weekly Roundup for MARCH 17, 2017: Recent Publications in Women’s Mental Health

  The most interesting article this week is from Dowlati and colleagues assessing the effectiveness of a nutritional supplement to decrease risk for postpartum blues.  While intriguing, it is not clear how effective this intervention will prove to be.   We will have a post on this paper next week.     Dowlati Y, Ravindran AV, […]

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Synthetic Oxytocin and Its Effect on Postpartum Mood and Anxiety

Often referred to as the “hormone of love,” oxytocin plays an important role in childbirth, maternal behavior, lactation, social affiliation, and sexual pleasure.  Levels of oxytocin, a neuropeptide produced by the hypothalamus and released into the bloodstream via the pituitary gland, rise around the time of delivery.   These levels remain high after delivery, specifically increasing […]

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Effectiveness of Psychological Interventions for Postpartum Depression in Primary Care

  Postpartum depression (PPD) has been identified as the “most under-recognized, under-diagnosed, and under-treated obstetrical complication in America”, affecting approximately 10-15% of new mothers. In addition to affecting maternal mental health during a critical time in a woman’s life, there are are a number of downstream effects associated with undiagnosed or untreated PPD such as […]

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Postpartum Progress: An Update and Other Resources

We were saddened to hear that Postpartum Progress, Inc. is in the process of shutting down.  Since its inception in 2004, Postpartum Progress has been an important resource for women with perinatal mood and anxiety disorders.  This organization — and all of the women behind it — have made such vital contributions in terms of […]

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