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Tag Archives | neonatal outcomes

What Causes Poor Neonatal Adaptation in Antidepressant-Exposed Infants?

It was back in 2005 when we first reported on studies which demonstrated an increased risk of “poor neonatal adaptation” in infants with prenatal exposure to selective serotonin reuptake inhibitor (SSRI) antidepressants in late pregnancy.  Since that time, reports consistently indicate that about 25%-30% of infants exposed to SSRIs late in pregnancy manifest symptoms of […]

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Preconception and Pregnancy Obesity Among Women with Psychiatric Disorders: An Important Risk Factor

Individuals with psychiatric disorders are at higher risk for obesity than the general population, as well as for medical comorbidity, such as diabetes, hypertension, hyperlipidemia, and cardiovascular disease.  Moreover, many medications for psychiatric disorders worsen this risk, particularly pharmacotherapy with atypical (second-generation) antipsychotic medications, used not only used for psychotic disorders, but increasingly as mood […]

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Risk of Neonatal Morbidity in Infants Exposed to SSRIs

A few days ago, an article was published in the journal Pediatrics on neonatal morbidity observed in children exposed to antidepressants.  Although this article is likely to find its way into the headlines, it is important to note that the information presented here is nothing new.  Similar to previous studies, the Pediatrics study reveals higher […]

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Baby Belly from Wikimedia Commons

Cannabis and Pregnancy: Increasing Use, Still Not Enough Data on Safety

We are seeing an increasing number of women in our clinic who are using marijuana on a regular basis — recreationally and medically prescribed — to help them manage various psychiatric symptoms, including depression and anxiety.  This is no surprise given that many states have or are now moving forward with the legalization of medical […]

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Baby Belly from Wikimedia Commons

Treatment of Opioid Addiction During Pregnancy: Buprenorphine

The use of opioid drugs in women of childbearing age has become a pressing public health concern.  It is clear that opiate use during pregnancy puts the mother and child at risk; opiate use during pregnancy has been associated with increased risk for oral clefts, neural tube defects, gastroschisis, congenital heart defects, and ophthalmic problems. […]

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Baby Belly from Wikimedia Commons

In Brief: Study Finds No Link Between Antipsychotics and Gestational Diabetes

Given the number of younger women using atypical antipsychotic medications, we need more accurate data regarding the reproductive safety of these medications. To better understand the link between antipsychotic medication and medical conditions associated with pregnancy, including gestational diabetes and hypertension, researchers compared pregnancy outcomes in 1,021 pregnant women taking antipsychotic medication to outcomes in […]

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Meta-Analysis: Antipsychotics and Pregnancy Outcomes

Second-generation or “atypical” antipsychotics, such as olanzapine (Zyprexa), aripiprazole (Abilify), and risperidone (Risperdal), are used far more frequently than are the first-generation or “typical” antipsychotics, such as haloperidol (Haldol). This is largely because the newer agents are associated with fewer side effects and, as a result, have been used for a wider spectrum of illnesses, […]

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You Asked: Is Duloxetine (Cymbalta) Safe To Use During Pregnancy?

You can find a more recent post on this topic here: Venlafaxine and Duloxetine: Pooled Analysis Shows No Increase in Risk of Malformations We receive a fair number of questions on the use of duloxetine during pregnancy.  Duloxetine (sold in the United Sates under the brand name of Cymbalta) is a serotonin-norepinephrine reuptake inhibitor (SNRI) […]

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PTSD in Veterans Increases Risk of Preterm Birth

Posttraumatic stress disorder (PTSD) is relatively common among pregnant and postpartum women. The lifetime prevalence of PTSD for women is about 10%.  PTSD is most prevalent among women of childbearing age and PTSD symptoms are common during pregnancy.  Earlier this year, we reported on a study which observed that women with a diagnosis of PTSD had an increased risk of preterm birth.  The risk was particularly high in those women with diagnoses of both PTSD and a major depressive episode; these women had a 4-fold increased risk of preterm birth.

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