• Monthly Archives: March 2015

    You Asked:  Is It Safe to Take Melatonin During Pregnancy?

    Many women experience some degree of sleep disturbance during pregnancy. For a significant number of women, the sleep disruption may be so severe as to require some type of intervention. In a previous post, we discussed the use of different types of medications to treat insomnia during pregnancy. While these drugs are highly effective, many women with sleep problems inquire about the use of “natural” agents, such as melatonin, during pregnancy.

    You Asked: Should Lamotrigine (Lamictal) Dose Be Adjusted During Pregnancy?

    For many women with bipolar disorder, lamotrigine (Lamictal) is an effective mood stabilizer.  Given its relatively favorable reproductive safety profile, lamotrigine is a reasonable option for women who require treatment with a mood stabilizer during pregnancy.

    What is S-Equol? Does It Really Work for Menopausal Symptoms?

    Approximately 70% of all women experience hot flashes and/or night sweats (also called vasomotor symptoms or VMS) during the menopause transition.  Although estrogen-containing hormone therapy is highly effective in managing these symptoms, various studies have raised concerns regarding the risks associated with prolonged use of hormone therapy and many women now use other non-hormonal options to manage their symptoms, including over-the-counter complementary and alternative medicines (CAMs), including soy isoflavones, black cohosh, and omega-3 fatty acids.  However, the data regarding the effectiveness of these alternative treatments has been mixed.

    Hormone Replacement Therapy: Some Risk But No Impact on Mortality

    While there are concerns regarding the risks associated with prolonged use of hormone replacement, an increasing number of studies suggest that the risk may be relatively low in certain settings.  A study presented this week at the Endocrine Society’s annual meeting which analyzed data from 43 randomized clinical trials suggests that menopausal hormone-replacement therapy does not appear to affect mortality either positively or negatively.

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