While there are concerns regarding the risks associated with prolonged use of hormone replacement, an increasing number of studies suggest that the risk may be relatively low in certain settings. A study presented this week at the Endocrine Society’s annual meeting which analyzed data from 43 randomized clinical trials suggests that menopausal hormone-replacement therapy does not appear to affect mortality either positively or negatively.
Menopausal Hormone Therapy and Mortality: A Systematic Review and Meta-Analysis (Abstract)
No Link Seen Between Hormone Replacement Therapy, Mortality (Medscape – Free Subscription)
Salpeter SR, Walsh JM, Greyber E, Ormiston TM, Salpeter EE. Mortality Associated with Hormone Replacement Therapy in Younger and Older Women: A Meta-analysis. Journal of General Internal Medicine. 2004;19(7):791-804. doi:10.1111/j.1525-1497.2004.30281.x.
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