SSRIs

What Causes Poor Neonatal Adaptation in Antidepressant-Exposed Infants?

It was back in 2005 when we first reported on studies which demonstrated an increased risk of “poor neonatal adaptation” in infants with prenatal exposure to selective serotonin reuptake inhibitor (SSRI) antidepressants in late pregnancy. [...]

By |2024-03-25T08:32:20-04:00February 8th, 2017|Pregnancy & Medications|Comments Off on What Causes Poor Neonatal Adaptation in Antidepressant-Exposed Infants?

Response to the New York Times Article on SSRIs and Pregnancy: Moving Toward a More Balanced View of Risk

We have received many emails and calls from colleagues and patients regarding the recent article on the safety of SSRI use during pregnancy published in the New York Times.  In this article, health writer Roni Caryn Rabin, detailed the risks associated with the use of antidepressants during pregnancy.

By |2015-08-05T10:29:23-04:00September 5th, 2014|Depressive Disorders, Psychiatric Disorders During Pregnancy, Treatment|Comments Off on Response to the New York Times Article on SSRIs and Pregnancy: Moving Toward a More Balanced View of Risk

Low Dose Paroxetine Improves Sleep in Postmenopausal Symptoms

Last year, the FDA approved the first non-hormonal treatment for hot flashes – a 7.5-mg formulation of the selective serotonin reuptake inhibitor (SSRI) paroxetine which was marketed under the name of Brisdelle. A new study [...]

By |2018-06-09T17:53:30-04:00August 25th, 2014|Medication, Menopausal Symptoms, Sleep Disorders, Treatment|Comments Off on Low Dose Paroxetine Improves Sleep in Postmenopausal Symptoms

Antidepressants and Weight Gain: Which Ones are the Worst Offenders?

Many women are understandably concerned about the risk of weight gain associated with antidepressants. It is difficult to advise them as to which antidepressants are less or more likely to cause weight gain, as there [...]

By |2014-06-15T21:22:16-04:00June 17th, 2014|Antidepressants, General, Outcomes|Comments Off on Antidepressants and Weight Gain: Which Ones are the Worst Offenders?

New Research from the CWMH: Venlafaxine As Effective As Estradiol for Hot Flashes

Various selective serotonin reuptake inhibitors (SSRIs), including citalopram (Celexa), escitalopram (Lexapro) and paroxetine (Paxil), have been shown to be effective for the treatment of menopausal vasomotor symptoms (VMS). Other studies have supported the efficacy of the serotonin–norepinephrine reuptake inhibitors (SNRIs) duloxetine (Cymbalta) and venlafaxine (Effexor). The FDA recently approved a 7.5-mg formulation of paroxetine (marketed as Brisdelle) as the first non-hormonal treatment of hot flashes.

By |2016-03-28T13:02:51-04:00June 2nd, 2014|Hormone Therapy, Medication, Menopausal Symptoms, Research at CWMH, Treatment, Vasomotor Symptoms|Comments Off on New Research from the CWMH: Venlafaxine As Effective As Estradiol for Hot Flashes

Good News: New Studies Show No Association Between Antidepressants and Risk of Autism

Two recent epidemiologic studies have demonstrated an association between prenatal exposure to selective serotonin reuptake inhibitor antidepressants (SSRIs) with autism spectrum disorders (ASD; Croen et al 2011, Rai et al, 2013).  One important imitation of these two studies is that parental psychiatric disorder in itself is associated with an increased risk of ASD in the offspring, and these studies could not distinguish between the effects of drug exposure and the consequences of the underlying maternal psychiatric illness.  Two new studies shed light on the association between prenatal antidepressant exposure and risk of autism spectrum disorder in the offspring.

By |2016-10-24T22:39:29-04:00February 5th, 2014|Pregnancy & Medications|Comments Off on Good News: New Studies Show No Association Between Antidepressants and Risk of Autism

FDA Approves Nonhormonal Drug for Hot Flashes: Low-Dose Paroxetine to be Marketed as Brisdelle

The FDA recently approved a 7.5-mg formulation of the selective serotonin reuptake inhibitor (SSRI) paroxetine mesylate for the treatment of hot flashes.   It will be marketed under the name of Brisdelle.

By |2015-08-06T09:25:00-04:00July 15th, 2013|Menopausal Symptoms, Vasomotor Symptoms|Comments Off on FDA Approves Nonhormonal Drug for Hot Flashes: Low-Dose Paroxetine to be Marketed as Brisdelle

Prenatal Exposure to Antidepressants and Risk of Autism

It is estimated that autism spectrum disorders (ASD) affect about 1% to 2% of children.  Research carried out in twins and families indicate that ASD is highly heritable; however, it is generally believed that while  genetic factors play an important role, there is an interplay between genetic and environmental factors in the etiology of this disorder.  Various environmental exposures have been implicated, including vaccinations, mercury, air pollution, insecticides, and infection.

By |2015-08-06T09:41:13-04:00May 29th, 2013|Antidepressants, Autism Spectrum Disorder, Neurodevelopmental Disorders, Outcomes, Pregnancy & Medications|Comments Off on Prenatal Exposure to Antidepressants and Risk of Autism
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