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Tag Archives | PPD

Pilot Study of Telephone-Delivered Interpersonal Therapy for Women with Postpartum Depression

It is clear that screening for perinatal depression substantially improves detection; however, screening alone does not appear to improve rates of treatment or outcomes.  What we find is that many, if not most, women with perinatal depression do not receive adequate care.  There appear to be many obstacles: stigma associated with mental illness, lack of […]

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Brexanolone: Related to Allopregnanolone, Effective for the Treatment of Postpartum Depression

In 2015, we first reported on SAGE-547 (SAGE Therapeutics), a new medication for the treatment of severe postpartum depression.  SAGE-547, now called brexanolone, is an allosteric modulator of GABAA receptors.  This drug was initially under investigation for the treatment of refractory seizure disorders but it turned out to be a good antidepressant.  The information we […]

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Perinatal Depression Screening Is Just The Start

The following post was first published in OB/GYN News. Please see our OB/GYN News archives here. Publish date:  March 3, 2017 Over the last decade, appreciation of the prevalence of perinatal depression – depression during pregnancy and/or the postpartum period – along with interest and willingness to diagnose and to treat these disorders across primary care, obstetric, […]

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Effectiveness of Psychological Interventions for Postpartum Depression in Primary Care

  Postpartum depression (PPD) has been identified as the “most under-recognized, under-diagnosed, and under-treated obstetrical complication in America”, affecting approximately 10-15% of new mothers. In addition to affecting maternal mental health during a critical time in a woman’s life, there are are a number of downstream effects associated with undiagnosed or untreated PPD such as […]

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Postpartum Progress: An Update and Other Resources

We were saddened to hear that Postpartum Progress, Inc. is in the process of shutting down.  Since its inception in 2004, Postpartum Progress has been an important resource for women with perinatal mood and anxiety disorders.  This organization — and all of the women behind it — have made such vital contributions in terms of […]

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Is Postpartum Depression on the Decline?

  Most studies over the last few decades have estimated the prevalence of postpartum depression (PPD) in the United States to be between 10% and 15%.  According to longitudinal data derived from the Pregnancy Risk Assessment Monitoring System (PRAMS), the prevalence in the US could be decreasing. Postpartum depression is common and associated with adverse […]

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Postpartum Specific Anxiety Scale: A New Instrument for Assessing Postpartum Anxiety

  Several studies suggest that postpartum anxiety is relatively common among postpartum women and may even be more common than depression.  Emerging evidence also suggests that a large number of postpartum women who do not meet diagnostic criteria for a specific anxiety disorder yet experience a clinically significant anxiety symptoms which are distinct from anxiety […]

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Improving Access to Mental Health Services: Could Lay Counselors Be Used to Treat Perinatal Depression?

About 15% of women suffer from perinatal depression — depression which emerges during pregnancy or the postpartum period; however, most women with perinatal depression do not receive any  type of treatment.  While we have made huge strides in increasing awareness of postpartum mental health issues, there are still significant obstacles to obtaining treatment.  Especially in […]

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Is BDNF a Biomarker for Depression During Pregnancy and the Postpartum Period?

Brain-derived neurotrophic factor (BDNF) is a growth factor which acts on neurons in both the central and peripheral nervous systems, promoting the survival of neurons and promoting the growth and differentiation of new neurons and synapses.  In the brain, it is most active in the hippocampus, cortex, and basal forebrain—areas important  to learning, memory, and […]

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Postpartum Depression in Women with No History of Psychiatric Illness

Most studies observe that about 15% of women experience postpartum depression (PPD).  For the majority of women who present with postpartum depression, the postpartum episode is not the first ever episode of depression and instead represents a recurrence.  These women report a pattern of recurrent depressive illness consisting of both puerperal and nonpuerperal episodes.   […]

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