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Tag Archives | perinatal depression

Fetal exposure to depression: How does ‘dose’ figure in?

The following post was first published in OB/GYN News. Please see our OB/GYN News archives here. Publish date: April 23, 2018 The last two decades have seen an ever-growing number of reports on risks of fetal exposure to medicines used to treat depression during pregnancy. These reports have described issues ranging from estimated risk of congenital malformations following […]

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One in Four Pregnant Women Suffers from Psychiatric Illness: How Can We Identify and Support Them?

  The title of the following article did not grab my attention; however, I discovered that this study, entitled Accuracy of the Whooley questions and the Edinburgh Postnatal Depression Scale in identifying depression and other mental disorders in early pregnancy published in the British Journal of Psychiatry, has some incredibly important findings. First of all, […]

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Worse Pregnancy Outcomes in Women with More Chronic Depressive Symptoms

Over the last decade we have seen multiple studies which have demonstrated an association between the use of antidepressants during pregnancy and increased risk of certain adverse outcomes, including preterm birth and low birth weight. But we have also seen quite a few studies which suggest that untreated maternal depression or anxiety may contribute to […]

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How Can We Ensure that Women with Perinatal Depression Get Treatment?

  The American College of Obstetricians and Gynecologists (ACOG) now recommends screening for perinatal depression, stating that “clinicians screen patients at least once during the perinatal period for depression and anxiety symptoms using a standard, validated tool.” Having the backing of ACOG is certainly a big step in the right direction.  But as we move […]

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History of Stillbirth Increases Risk for Depression, Anxiety During Subsequent Pregnancies

  Perinatal loss is a traumatic event for women and their families.  While we clearly understand the potential for perinatal loss to cause significant emotional consequences, we have relatively little data on the prevalence of anxiety and depressive illness in this population of women. A recent study surveyed 609 women who had experienced a stillbirth […]

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Perinatal Depression: Can We Predict Who is At Risk for Suicide?

  It is estimated that suicide accounts for about 10% of all maternal deaths. While we have a fair amount of information to help us predict which women are at risk for depression during pregnancy and the postpartum period, few studies have identified risk factors for suicide in this vulnerable population. Suicidal ideation is fairly […]

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Brexanolone: Related to Allopregnanolone, Effective for the Treatment of Postpartum Depression

In 2015, we first reported on SAGE-547 (SAGE Therapeutics), a new medication for the treatment of severe postpartum depression.  SAGE-547, now called brexanolone, is an allosteric modulator of GABAA receptors.  This drug was initially under investigation for the treatment of refractory seizure disorders but it turned out to be a good antidepressant.  The information we […]

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Perinatal Depression Screening Is Just The Start

The following post was first published in OB/GYN News. Please see our OB/GYN News archives here. Publish date:  March 3, 2017 Over the last decade, appreciation of the prevalence of perinatal depression – depression during pregnancy and/or the postpartum period – along with interest and willingness to diagnose and to treat these disorders across primary care, obstetric, […]

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Postpartum Progress: An Update and Other Resources

We were saddened to hear that Postpartum Progress, Inc. is in the process of shutting down.  Since its inception in 2004, Postpartum Progress has been an important resource for women with perinatal mood and anxiety disorders.  This organization — and all of the women behind it — have made such vital contributions in terms of […]

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How Can We Screen for Perinatal Depression in the Developing World?

While perinatal mood and anxiety disorders (PMAD) have a global footprint, the majority of research related to this group of illnesses has come largely from more affluent, Westernized countries.  Similarly, the tools used to detect and screen for PMADs were developed and tested in these Westernized countries.   The instrument most commonly used to detect […]

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