perinatal depression

One in Four Pregnant Women Suffers from Psychiatric Illness: How Can We Identify and Support Them?

  The title of the following article did not grab my attention; however, I discovered that this study, entitled Accuracy of the Whooley questions and the Edinburgh Postnatal Depression Scale in identifying depression and other [...]

Worse Pregnancy Outcomes in Women with More Chronic Depressive Symptoms

Over the last decade we have seen multiple studies which have demonstrated an association between the use of antidepressants during pregnancy and increased risk of certain adverse outcomes, including preterm birth and low birth weight. [...]

History of Stillbirth Increases Risk for Depression, Anxiety During Subsequent Pregnancies

Perinatal loss is a traumatic event for women and their families.  While we clearly understand the potential for perinatal loss to cause significant emotional consequences, we have relatively little data on the prevalence of anxiety [...]

Brexanolone: Related to Allopregnanolone, Effective for the Treatment of Postpartum Depression

In 2015, we first reported on SAGE-547 (SAGE Therapeutics), a new medication for the treatment of severe postpartum depression.  SAGE-547, now called brexanolone, is an allosteric modulator of GABAA receptors.  This drug was initially under [...]