maternal depression

Worse Pregnancy Outcomes in Women with More Chronic Depressive Symptoms

Over the last decade we have seen multiple studies which have demonstrated an association between the use of antidepressants during pregnancy and increased risk of certain adverse outcomes, including preterm birth and low birth weight. [...]

Brexanolone: Related to Allopregnanolone, Effective for the Treatment of Postpartum Depression

In 2015, we first reported on SAGE-547 (SAGE Therapeutics), a new medication for the treatment of severe postpartum depression.  SAGE-547, now called brexanolone, is an allosteric modulator of GABAA receptors.  This drug was initially under [...]