• major depression

    Is Postpartum Depression a Distinct Subtype of Depression? Taking a Closer Look at the Amygdala

    While many women with postpartum depression (PPD) have had previous episodes of major depression and will go on to have other episodes of depression outside of the postpartum period, many have questioned whether postpartum depression [...]

    Exposure to Antidepressants During Pregnancy: Less Impact on Long Term Outcomes Than Previously Reported

    In the current issue of the Journal of Clinical Psychiatry, Rommel and colleagues present a systematic review examining the long-term effects of prenatal exposure to antidepressants on physical, neurodevelopmental, and psychiatric outcomes in children [...]

    PCOS Carries Increased Risk for Bipolar Disorder, Risk Reduced with Metformin

    Polycystic Ovarian Syndrome (PCOS) is the most common endocrine-related dysfunction in women of reproductive age.  Multiple studies have observed a higher prevalence of psychiatric illness, including depressive disorders, anxiety disorders, and bipolar disorder in [...]

    Brexanolone: Related to Allopregnanolone, Effective for the Treatment of Postpartum Depression

    In 2015, we first reported on SAGE-547 (SAGE Therapeutics), a new medication for the treatment of severe postpartum depression.  SAGE-547, now called brexanolone, is an allosteric modulator of GABAA receptors.  This drug was initially under [...]

    CBT for Depression During Pregnancy: Good for Moms, Good for Babies

    Australian researchers have developed a cognitive behavioural therapy (CBT) treatment intervention for antenatal depression and anxiety.  Beating the Blues Before Birth, to be delivered as individual therapy, was adapted from a 12-session group intervention for [...]

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