For women who require treatment with quetiapine during pregnancy, the available reproductive safety data are generally reassuring. The largest body of evidence does not suggest a meaningful increase in major congenital malformations, while metabolic effects, particularly gestational diabetes, remain an important consideration.
Exposure to long-acting injectable and oral second-generation antipsychotics during pregnancy was associated with similar obstetric outcomes in a large retrospective study.
In this retrospective study of Taiwanese women using antipsychotic medications there was no observed increase in risk of metabolic complications.
Second-generation antipsychotic medications associated with high metabolic risk (quetiapine, olanzapine, and clozapine) were associated with increased risk of gestational diabetes; other antipsychotics were not.
SSRI and SNRI antidepressants were not associated with an increased risk for gestational diabetes.
Over a year ago, we wrote our first post on COVID-19, and it is hard to believe that we are still very much in the midst of a pandemic. Since that time, we have [...]
Given the number of younger women using atypical antipsychotic medications, there is an urgent need for more accurate data regarding the reproductive safety of these medications. One important question is whether these newer antipsychotic [...]
Individuals with psychiatric disorders are at higher risk for obesity than the general population, as well as for medical comorbidity, such as diabetes, hypertension, hyperlipidemia, and cardiovascular disease. Because obesity is associated with an [...]
According to recent findings published in Diabetic Medicine, women who develop gestational diabetes may be more likely to experience depression during pregnancy and after delivery, compared to women without gestational diabetes. Over the years, we [...]
A recent study looks at the risk for gestational diabetes in women taking antidepressants during pregnancy. In this study from Quebec, women with gestational diabetes mellitus (GDM) diagnosed after the 20th week of pregnancy [...]
