congenital malformation

SSRI Antidepressants Not Associated with Cardiovascular Defects

Over the last few years, we have reported on several studies which have suggested an  increased risk of certain types of cardiovascular malformations among children exposed to selective serotonin reuptake inhibitors (SSRIs) during pregnancy. The [...]

By |2016-03-28T13:55:55-04:00July 9th, 2014|Antidepressants, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on SSRI Antidepressants Not Associated with Cardiovascular Defects

SSRIs and Chiari Malformations

A recent study from researchers at the University of North Carolina reports that the children of depressed mothers treated with selective serotonin reuptake inhibitors (SSRIs) during pregnancy were more likely to develop Chiari type 1 malformations than were the children of mothers with no history of depression.

By |2014-06-17T10:16:50-04:00June 16th, 2014|Antidepressants, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on SSRIs and Chiari Malformations

SSRIs and Cardiovascular Malformations: Another Look

Over the last few years, we have reported on several studies which have suggested an increased risk of certain types of cardiovascular malformations among children exposed to selective serotonin reuptake inhibitors (SSRIs) during pregnancy.  The first reports suggested a link between cardiac septal defects and exposure to paroxetine; subsequent studies have also shown elevated risks with the other SSRIIs. 

By |2015-08-10T14:03:04-04:00November 20th, 2012|Antidepressants, Pregnancy & Medications, Risk of Malformations|Comments Off on SSRIs and Cardiovascular Malformations: Another Look

Zolpidem (Ambien) in Pregnancy: Is it Safe?

It is estimated that up to 95% of women experience some type of sleep disturbance during pregnancy.  While for many women the insomnia is relatively benign and may respond to simple interventions, other women experience more severe insomnia which has a significant impact on their quality of life and ability to function.  While zolpidem (Ambien), a sedative-hypnotic agent used for the short-term treatment of insomnia, is commonly prescribed in pregnant women, the information regarding its reproductive safety has been sparse.

By |2015-08-13T11:45:40-04:00November 22nd, 2010|Pregnancy & Medications, Sleep Disorders|Comments Off on Zolpidem (Ambien) in Pregnancy: Is it Safe?
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