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Tag Archives | bipolar disorder

New Research from the CWMH: Patterns of Atypical Antipsychotic Use During Pregnancy

  The use of the newer “atypical” or second-generation antipsychotic agents is increasing.  Atypical antipsychotics are now used to treat a spectrum of psychiatric disorders, including schizophrenia, bipolar disorder, major depression, PTSD and other anxiety disorders.  Using data from the Medicaid Analytic eXtract (MAX) data of pregnant women who delivered infants born between 2001 and […]

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Clinical Guidelines for Lithium Dosing During Pregnancy

  We have an abundance of articles which address the impact of psychotropic medications on pregnancy.  Much less research, however, has focused on how pregnancy may affect how these medications work. Physiologic changes take place during pregnancy which may affect the absorption, distribution, metabolism, and elimination of medications.  These pharmacokinetic changes may result in lower […]

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Postpartum Psychosis: Ten Things You Need to Know

Because postpartum psychosis is a relatively rare event, we do not have as much information on this illness as we have on postpartum depression.  In addition, most of the literature we have on postpartum psychosis is not new.  The American Journal of Psychiatry has just published an excellent and well-researched review on the topic online […]

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Clinical Case: Breastfeeding in a Woman with Bipolar Disorder

Ms. C is a woman with a long history of bipolar disorder, dating back to her teen years.  Because she experienced recurrent hypomania and mania every time she attempted to discontinue her treatment, she and her psychiatrist decided that she would remain on her regular regimen of medications during pregnancy and the postpartum period, which […]

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Atypical Antipsychotics and Breastfeeding

Women with bipolar disorder are at a higher risk for relapse during pregnancy and that the risk is even higher during the postpartum period.  In addition, women with bipolar disorder are more vulnerable to postpartum psychosis.  It is for these reasons that we typically recommend that women with bipolar disorder maintenance treatment with a mood […]

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Credit: Depressed Mother from Wikimedia Commons

Risk of Postpartum Illness in Women with Histories of Bipolar Disorder or Postpartum Psychosis

Various studies have demonstrated that women with histories of either bipolar disorder or postpartum psychosis are at high risk for postpartum relapse.  While we recognize the risk as being “high”, estimations of the risk for relapse vary widely.   For example, a Swedish birth register study estimated the risk for postpartum relapse to be 8.5% […]

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Are Women with Bipolar Disorder at Risk of Illness After Miscarriage?

Women with bipolar disorder are at significant risk for recurrent illness during the postpartum period.  After miscarriage, an event which is associated with both hormonal changes and psychological complexity, is the risk for recurrent illness also increased? This question was addressed by researchers with a retrospective review of 1,283 women with “broadly defined bipolar disorder”. […]

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Credit: Depressed Mother from Wikimedia Commons

What Screening Tools Identify Postpartum Women with Bipolar Disorder?

Women with bipolar disorder (BD) are at extremely high risk for postpartum psychiatric illness, specifically postpartum psychosis.  While the American College of Obstetrics and Gynecology now recommends that all women be screened for depression during pregnancy and the postpartum period, we have little information regarding the screening tools that are best suited for the identification […]

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Conference News from ECNP: High Risk of Psychopathology in the Offspring of Parents with Bipolar Disorder and Schizophrenia

Children whose parents have either schizophrenia or bipolar disorder are at high risk for psychopathology.  There are genetic factors which influence vulnerability to illness, but environmental influences also play a role.  Data presented at the 28th European College of Neuropsychopharmacology (ECNP) Congress in Amsterdam (reviewed in Medscape) suggest that  psychopathology in this group of children […]

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Lithium: Women More Vulnerable to Adverse Effects Than Men

Lithium is one of the most effective treatments for patients with bipolar disorder.  Its use, however, is limited by its potential for serious long-term adverse events, including renal, thyroid, and parathyroid dysfunction. A recent study published in Lancet helps to put these various risks into perspective and indicates that women may be more vulnerable to […]

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