aripiprazole - MGH Center for Women's Mental Health

Pilot Study: Aripiprazole Added to Antidepressants for Postpartum Depression

Augmentation strategies can be used to optimize response in patients with major depressive disorder (MDD) who have not responded adequately to antidepressant monotherapy; however, we have no data on the use of adjunctive treatments in women with postpartum depression (PPD). A recent study tested the effectiveness of antidepressant augmentation with aripiprazole (Abilify) in a cohort of 10 women with onset of a depression within 3 months of the birth of a healthy, close-to-term baby.

By MGH Center for Women's Mental Health|2014-10-23T14:38:03-04:00October 27th, 2014|Postpartum Psychiatric Disorders, Women's Mental Health|0 Comments

Antipsychotics and Pregnancy Part 2: Preliminary Data from the MGH Pregnancy Registry

This is the second part of a two part series on the use of antipsychotic medications during pregnancy. Read Part 1 here, which reviews data from the Australian antipsychotic registry.

By MGH Center for Women's Mental Health|2016-03-28T13:23:55-04:00August 6th, 2014|New Research, Psychiatric Disorders During Pregnancy|2 Comments

More Data on the Use of Atypical Antipsychotics During Pregnancy

Despite the use of the newer “atypical” antipsychotic agents to treat a spectrum of psychiatric disorders, including schizophrenia, bipolar disorder, major depression, PTSD and other anxiety disorders, three is relatively little data on the reproductive safety of these newer atypical agents.

By Ruta Nonacs, MD PhD|2024-04-14T16:17:26-04:00September 11th, 2013|Psychiatric Disorders During Pregnancy|0 Comments

Prevalence and Trends in the Use of Antipsychotic Medications during Pregnancy

Since their introduction in the 1990s, atypical (second-generation) antipsychotics have replaced typical (first generation) antipsychotics as the first-line treatment for schizophrenia and related psychotic disorders. These drugs are widely used by reproductive age women across many other disease states including bipolar disorder, major depression and anxiety disorders as either primary or adjunctive treatments.

By Ruta Nonacs, MD PhD|2024-04-14T16:17:44-04:00June 10th, 2013|New Research, Psychiatric Disorders During Pregnancy|0 Comments

Atypical Antipsychotic Medications: What Do We Know About Their Reproductive Safety?

Atypical antipsychotic medications are commonly used for the treatment of schizophrenia and bipolar disorder. Despite the increasing use of these medications in women of child-bearing age, there is still relatively little data regarding the reproductive safety and long-term neurodevelopmental effects of these medications. A recent study assessed the development of 76 infants with fetal exposure to atypical antipsychotics.

By MGH Center for Women's Mental Health|2015-08-06T10:39:32-04:00May 15th, 2013|Psychiatric Disorders During Pregnancy|0 Comments