• women’s mental health

    Research from the CWMH: Are Omega-3 Fatty Acids Effective for Menopausal Vasomotor Symptoms?

    Approximately seventy percent of all women experience hot flashes and/or night sweats during the menopause transition (Stearns et al, 2002).  Until recently, estrogen therapy was the treatment of choice for most women who sought treatment for hot flashes, but today many women are pursuing non-hormonal treatments, including over-the-counter complementary and alternative medicines (CAMs) for the treatment of these symptoms. 

    Soy Supplements for Menopausal Symptoms: Higher Doses and More Frequent Dosing May Help

    Studies assessing the effectiveness of complementary and alternative medicines (CAM) for the treatment of menopause-related hot flashes have yielded conflicting results.  Most studies have demonstrated that treatments such as soy and black cohosh are not likely to be effective in most women; however, a new study suggests that women who take higher doses (100 to 200 mg)of isoflavones and more frequent dosing (2-3 times per day) may experience a greater reduction in the frequency of hot flashes.

    Remote Enrollment Initiated in MGH Study Assessing Mood Symptoms Across Infertility Treatment

    We are pleased to announce the recent launch of an exciting new research initiative that is being conducted by the Massachusetts General Hospital Center for Women’s Mental Health.  The Symptom Tracking in Assisted Reproductive Technologies study (START study) will focus on understanding the risk factors for depressive relapse in women undergoing infertility treatments.  There has been a growing request in our clinical work to address the needs of women undergoing infertility treatments.  It is our hope that such a study will provide important information on the course and risk of depression in women undergoing fertility treatment and thus inform clinical care.

    Omega-3 Fatty Acids and Perinatal Depression: Maybe or Maybe Not

    The omega-3 fatty acids, including eicosapentaenoic acid (EPA) and docosahexanoic acid (DHA), have a broad range of health benefits and may be beneficial for the treatment of mood disorders.  Because during pregnancy omega-3 fatty acids are diverted to the developing fetus, some women may develop a deficiency of omega-3 fatty acids during pregnancy.  Previous studies have shown that pregnant women with lower levels of DHA may be more vulnerable to depressive symptoms.  Several small studies have attempted to use omega-3 fatty acids to treat perinatal depression but have yielded inconsistent findings.  

    Being a Mother Scale: A New Instrument for Assessing the Experience of Motherhood

    In our weekly clinical rounds, we recently discussed how motherhood is such a unique and personal experience for each woman. Often it is assumed that this transition into a new role is easy when for many it is not. How we assess a woman's experiences during the postpartum period is often limited to just her mood.  I recently came across a new self-report instrument, The Being a Mother Scale (BaM-13) developed by Stephen Matthey which attempts to assess the “wider domain of the woman’s experience of motherhood” rather than just the presence or absence of a postpartum mood disorder. 

    Hyperemesis Gravidarum and Depression: Which Comes First?

    Most women have some nausea or vomiting, or "morning sickness", during the first trimester of pregnancy.  Some women, however, have a more severe and persistent pattern of nausea and vomiting called hyperemesis gravidarum (HG).  A new study demonstrates, not so surprisingly, that depression is more common in women suffering from HG.   

    No Increase in Risk of Infant Mortality in Women Taking SSRIs During Pregnancy

    While there has been a great deal of attention paid to the risks of exposure to antidepressants, particularly the selective serotonin reuptake inhibitors (SSRIs), during pregnancy, there has been comparatively little information on the risk of stillbirth and infant mortality in this population.  In a recent population-based cohort study utilizing data from all Nordic countries (Denmark, Finland, Iceland, Norway, and Sweden), researchers assessed the risk of stillbirth and infant mortality associated with the use of SSRIs during pregnancy.

    Dr. Lee Cohen in Ob-Gyn News: Using SSRIs in Pregnancy

    Over the last decade, attention in the medical literature has gathered logarithmically to focus on potentially efficacious treatments for perinatal depression. Studies of relevant databases, editorials, and various reviews have addressed the reproductive safety concerns of antidepressant treatments, particularly selective serotonin reuptake inhibitors (SSRIs) on one hand, and the impact of untreated maternal psychiatric illness on fetal and maternal well-being on the other.

    Mindfulness Yoga for the Treatment of Depression During Pregnancy: A Pilot Study

    Over the past decade, the clinical literature has published many studies documenting the psychosocial and health benefits of various mind-body interventions.  Mindfulness-based interventions have been shown to reduce stress, to improve coping skills, and to promote feelings of well-being.  Mindfulness-Based Cognitive Therapy (MBCT) is a new psychotherapeutic treatment which has been shown to reduce depressive symptoms and to reduce the risk of depressive relapse. 

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