perimenopause - MGH Center for Women's Mental Health

Yaz and Other Oral Contraceptives Will Carry a New Warning Label

The FDA will require Yaz, Yasmin and several other newer oral contraceptives to carry new warning labels that detail the potential risk of venous thromboembolism (VTE or blood clots). All oral contraceptives increase the risk of blood clots; however, recent studies have suggested that birth control pills containing drospirenone, a synthetic form of the hormone progesterone, may carry a slightly increased risk of VTE, compared with older birth control pills. The FDA estimates that over a one year period, 10 in 10,000 women taking an oral contraceptive with drospirenone would develop a blood clot , as compared to about 6 in 10,000 women taking older contraceptives.

By MGH Center for Women's Mental Health|2015-08-12T15:27:01-04:00May 24th, 2012|Menopausal Symptoms, PMS and PMDD|0 Comments

Heavy Menstrual Bleeding More Common in Midlife Women with Histories of Depression

Menstrual problems are common among premenopausal women and become more frequent with increasing reproductive age, especially just before and during perimenopause. In the Study of Women's Health Across the Nation, a multisite study of menopause and aging, information regarding menstrual history was collected in a total of 934 premenopausal and early perimenopausal women between the ages of 42 and 52. History of major depression was associated with an increased likelihood of heavy bleeding (odds ratio, 1.89), adjusting for recent major depression, menopause status, and other confounding factors. History of depression was not associated with other abnormal bleeding or premenstrual symptoms. Future longitudinal studies are needed to explore why past depression increases the likelihood of subsequent heavy menstrual bleeding in midlife women. One possibility is that irregular fluctuations in estrogen levels may be responsible for both abnormal menstrual bleeding, as well as the dysregulation of neurotransmitter systems that mediate depressive symptoms.

By MGH Center for Women's Mental Health|2015-08-12T16:16:56-04:00May 22nd, 2012|Menopausal Symptoms|1 Comment

Aerobic Training Improves Menopausal Symptoms and Mood

In this randomized clinical trial, 154 sedentary, symptomatic women were randomly assigned to an aerobic training or a control group. The intervention included unsupervised aerobic training for 50 minutes four times weekly for 24 weeks, whereas the control group attended health lectures twice a month. Night sweats, mood swings, and irritability were reduced more among the women in the intervention group than in the control group.

By MGH Center for Women's Mental Health|2015-08-12T16:51:26-04:00March 12th, 2012|Menopausal Symptoms|0 Comments

The Truth About Bioidentical Hormones

In increasing numbers, women who are candidates for hormonal replacement therapy are requesting “bioidentical” rather than synthetic hormones. Although there is a tendency to think of bioidentical hormones as “all-natural”, they, like synthetic hormones, are manufactured in the laboratory. In contrast to synthetic hormones, they are chemically identical to the hormones produced by the human body; synthetic hormones are structurally different yet are designed to have similar biological effects as naturally produced hormones.

By MGH Center for Women's Mental Health|2015-04-14T22:59:40-04:00November 23rd, 2009|Menopausal Symptoms|5 Comments

Hot Flashes or Depression: Which Comes First?

Hot flashes and depression are both common symptoms of the menopause transition. Several studies have found a relationship between depression and hot flashes: depressed women are more likely to experience hot flashes and women with hot flashes are more likely to have depression. Other studies have found no association between hot flashes and depression.

By MGH Center for Women's Mental Health|2015-08-12T15:09:09-04:00September 14th, 2009|Menopausal Symptoms|0 Comments

Depression and Menopausal Symptoms Go Together

It is well established that women are at increased risk for developing depression compared to men. It has been hypothesized that this vulnerability to depression may be hormonally mediated, and several longitudinal studies have documented an increased risk of depressive symptoms during perimenopause or the menopausal transition. Based on the results of two prospective cohort studies, approximately one-third of women will develop their first episode of depression during the menopausal transition. (Cohen LS et al 2006, Freeman EW et al 2006).

By MGH Center for Women's Mental Health|2015-08-12T14:58:10-04:00August 17th, 2009|Menopausal Symptoms|3 Comments

Sleep Problems in Menopausal Women

Peri- and post-menopausal women frequently complain of insomnia or poor sleep quality. Sleep disturbance is often attributed to nocturnal hot flashes; however, a recent study from researchers at Wayne State University School of Medicine suggests that about half of these women may have a primary sleep disorder.

By MGH Center for Women's Mental Health|2015-07-28T10:44:52-04:00November 3rd, 2007|Menopausal Symptoms|11 Comments

Perimenopause May Be a Time of Risk for New Onset Depression

The transition to menopause has typically been considered a time when women may be more vulnerable to mood changes. There have been inconclusive data, however, as to whether women with no lifetime history of depression transitioning to menopause are at increased risk for developing an episode of major depression.

By MGH Center for Women's Mental Health|2018-07-11T13:57:12-04:00February 10th, 2007|Menopausal Symptoms, New Research|0 Comments

Perimenopause: A Time of Risk for Depression

More than 50 percent of women experience some perimenopausal symptoms, including hot flushes, night sweats, and sleep disturbance, before reaching the menopause. A recent article from Aetna Intelihealth notes that many women may also experience depression. In a study form Dr. Claudio Soares, women with clinically confirmed perimenopause were interviewed:

By MGH Center for Women's Mental Health|2015-07-22T15:15:13-04:00October 22nd, 2005|Menopausal Symptoms|0 Comments