Is It Safe to Use Hydroxyzine During Pregnancy?
Hydroxyzine is used frequently for the management of anxiety and sleep problems during pregnancy. However, there is limited information regarding its reproductive safety.
Essential Reads: Duloxetine and Pregnancy (2021)
In this large study with over 1500 exposures, duloxetine exposure during the first trimester does not appear to increase risk of major malformations.
Essential Reads: More Data on ADHD Medications and Pregnancy
Women with attention-deficit/hyperactivity disorder (ADHD) often discontinue psychostimulant medications during pregnancy, especially if they have milder symptoms. While this approach makes sense in terms of limiting unnecessary exposures in women with what appears to [...]
Clinical Update 2020: New Data on Duloxetine and Pregnancy
A few weeks ago, we published a clinical update for duloxetine (Cymbalta) and pregnancy, stating that there was little new to report since we last covered the topic in 2015. It is somewhat amusing [...]
Clinical Update 2020: Duloxetine and Pregnancy
Women face difficult choices when deciding whether or not to continue psychiatric medications during pregnancy. For many years, we have typically recommended the older antidepressants, including the selective serotonin reuptake inhibitors or SSRIs such [...]
Preliminary Data Raises Concerns About Modafinil Use in Pregnancy
Modafinil (brand name Provigil) is a wake-promoting agent which is used to treat sleepiness due to narcolepsy, shift work sleep disorder, or obstructive sleep apnea. It is also used to in others settings, often [...]
New Research from the CWMH: Prenatal Exposure to Atypical Antipsychotics Does Not Increase Risk of Malformations
The use of the newer “atypical” or second-generation antipsychotic agents continues to increase. These medications are used to treat a spectrum of psychiatric disorders, including schizophrenia, bipolar disorder, major depression, PTSD and anxiety disorders. Although [...]
New Research from the CWMH: Evaluating the Risk of Major Malformations in Children Prenatally Exposed to Atypical Antipsychotics
Despite the increasing use of the newer “atypical” or second-generation antipsychotic agents to treat a spectrum of psychiatric disorders, including schizophrenia, bipolar disorder, major depression, PTSD and other anxiety disorders, we have relatively little data [...]
New Research from the CWMH: Newer Antipsychotics and Pregnancy
Despite the increasing use of the newer “atypical” or second-generation antipsychotic agents to treat a spectrum of psychiatric disorders, including schizophrenia, bipolar disorder, major depression, PTSD and other anxiety disorders, we have relatively little data [...]
Venlafaxine and Duloxetine: Pooled Analysis Shows No Increase in Risk of Malformations
Women face difficult choices when deciding whether or not to continue psychiatric medications during pregnancy. This choice can be especially difficult for women taking newer medications which lack adequate reproductive safety data. While we have [...]