herbal supplements

Preliminary Study: Folic Acid Reduces Risk for Autism in Kids Prenatally Exposed to Antiepileptic Drugs

Several studies have observed that fetal exposure to the antiepileptic drug (AED), valproic acid (Depakote), may significantly increase the risk of having a child with an autism spectrum disorder.  In contrast, exposures to other AEDs, [...]

By |2025-06-26T09:07:59-04:00August 10th, 2016|Pregnancy & Medications|Comments Off on Preliminary Study: Folic Acid Reduces Risk for Autism in Kids Prenatally Exposed to Antiepileptic Drugs

Folic Acid Supplements Before and After Conception: Prevention of Autism

In a recent editorial in The Annals of Internal Medicine entitled “Enough Is Enough: Stop Wasting Money on Vitamin and Mineral Supplements,” authors make a case that multivitamins are not a good value (Dec 17, 2013 issue).  This editorial was based on new research that demonstrated that there was no association between multivitamin use and rates of mortality, cognitive decline and recurrent cardiovascular events in three different studies.  The assertion that multivitamins are not worth the money was widely reported in the media.

By |2016-05-15T20:32:46-04:00January 29th, 2014|Neurodevelopmental Disorders, Prevention, Psychiatric Disorders During Pregnancy, Risk of Malformations|Comments Off on Folic Acid Supplements Before and After Conception: Prevention of Autism

L-Methylfolate for the Treatment of Depression: Can We Use it During Pregnancy?

Last summer, we posted a blog about using folate to treat (and perhaps prevent) depression in women of childbearing age.  Supporting that recommendation are the several reports indicating that people with lower folate levels are at higher risk of major depression or may experience more severe depressive symptoms.  Other studies have indicated that in folate-deficient patients, antidepressants may be less effective or may take longer to take effect.

By |2018-06-15T10:45:27-04:00March 25th, 2013|Outcomes, Pregnancy & Medications|Comments Off on L-Methylfolate for the Treatment of Depression: Can We Use it During Pregnancy?

Folic Acid and Risk of Perinatal Depression: Is There an Association?

Recent reports suggest that people with lower folate levels are at higher risk of major depression or may experience more severe depressive symptoms.  Other studies indicate that in folate deficient patients, antidepressants may be less effective or may take longer to take effect.  In addition, some clinical trials have shown that folate may have a therapeutic effect on depression, either when taken alone or in combination with an antidepressant.

By |2015-08-12T12:25:29-04:00July 25th, 2012|Depressive Disorders, Prevalence & Risk Factors, Psychiatric Disorders During Pregnancy|Comments Off on Folic Acid and Risk of Perinatal Depression: Is There an Association?

Premenstrual Symptoms: What About Herbal Supplements?

Many women with PMS and PMDD ask about herbal remedies for the treatment of their symptoms.  WebMD recently reviewed this topic. The supplements most commonly mentioned for the treatment of PMS include chasteberry, evening primrose oil, Gingko biloba, St. John’s wort, and dandelion leaf.  Some important things to remember:

By |2015-08-12T14:02:34-04:00July 3rd, 2012|Alternative & Complementary, PMS & PMDD, Treatment|Comments Off on Premenstrual Symptoms: What About Herbal Supplements?

Pomegranate Seed Oil for Hot Flashes?

While phytoestrogens have gained attention as possible alternatives to hormone therapy for the treatment of menopausal symptoms, placebo-controlled studies have yielded mixed results.  Pomegranate seed oil is a very rich source of phytoestrogens.  In this prospective randomized, placebo-controlled, double-blinded trial, 81 postmenopausal women received two daily doses of either 30 mg pomegranate seed oil (PGS) or placebo.  The frequency of hot flashes decreased by 38.7% (P < 0.001) after 12 weeks of treatment with pomegranate seed oil and by 25.6% in the placebo group (P < 0.01). However, the difference between the two groups was not statistically significant (P = 0.17).   The authors suggest that it may take a longer period of observation to demonstrate a difference between pomegranate seed oil and placebo.

By |2015-08-12T15:25:03-04:00May 29th, 2012|Alternative & Complementary, Menopausal Symptoms, Treatment, Vasomotor Symptoms|Comments Off on Pomegranate Seed Oil for Hot Flashes?

St. John’s Wort: Is it Safe for Pregnancy?

St. John's wort (Hypericum perforatum) is an herbal preparation which has been shown, in some studies, to be effective for the treatment of mild to moderate depressive symptoms. St. John's wort is now one of the most commonly used herbal products in the United States and is widely used in Europe.

By |2015-08-11T14:14:20-04:00August 5th, 2008|Antidepressants, Depressive Disorders, Pregnancy & Medications, Risk of Malformations|Comments Off on St. John’s Wort: Is it Safe for Pregnancy?
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