This register-based cohort study from Denmark of 503,158 clinically recognized pregnancies observed little or no risk of teratogenesis associated with first trimester exposure to antipsychotic medications.
Modafinil (brand name Provigil) and armodafinil (Nuvigil) are wake-promoting agents used to treat sleepiness due to narcolepsy, shift work sleep disorder, or obstructive sleep apnea. They are also used in other settings, often in [...]
No major malformations were associated with olanzapine exposure during the first trimester of pregnancy.
All of our information on the reproductive safety of medications comes from non-randomized studies. However, many of these studies fail to take into consideration other factors associated with maternal psychiatric illness which may also affect outcomes.
Although a small sample, no major malformations were observed in a prospectively followed cohort of women with first trimester exposure to buspirone.
The most recent publication from the National Pregnancy Registry focuses on overall risk of malformations associated with the class of antipsychotic medications.
Despite the increasing use of the newer atypical or second-generation antipsychotic agents to treat a spectrum of psychiatric disorders, including psychotic disorders, bipolar disorder, major depression, PTSD and other anxiety disorders, we have relatively little [...]
Previous studies have suggested a link between opioid exposure during pregnancy and increased risk of certain major malformations, including neural tube defects. A recent study from Bateman and colleagues assesses the risk of major malformation [...]
This is the first installment of a new feature on our website: ESSENTIAL READS This is a kind of shortcut which allows you to find the most relevant reviews and articles in reproductive psychiatry. [...]
As soon as we published this article on the use of modafinil during pregnancy, another study was published which included data on the reproductive safety of modafinil and armodafinil from the US Provigil/Nuvigil Pregnancy [...]
