• autism spectrum disorders

    Prenatal Exposure to Antidepressants and Risk of Autism

    It is estimated that autism spectrum disorders (ASD) affect about 1% to 2% of children.  Research carried out in twins and families indicate that ASD is highly heritable; however, it is generally believed that while  genetic factors play an important role, there is an interplay between genetic and environmental factors in the etiology of this disorder.  Various environmental exposures have been implicated, including vaccinations, mercury, air pollution, insecticides, and infection.

    Exposure to Valproic Acid and Increased Risk of Autism Spectrum Disorders

    There have long been concerns regarding the use of the anticonvulsant valproate (Depakote, VPA) during pregnancy. First trimester use of valproate has been associated with a 3-5% risk of neural tube defects, as well as an increased risk of other malformations affecting the heart and other organ systems.  Multiple reports have also indicated that in utero exposure to valproate may also negatively affect cognitive development.

    Another Good Reason for Women of Childbearing Age to Take Folic Acid

    A new study reports that women taking folic acid before pregnancy were less likely to give birth to children with autism. The risk of having a child with autism was reduced by 40% among women who had taken folic acid supplements from four weeks prior to conception and continuing eight weeks into the pregnancy. 

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