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Archive | pregnancy

Is Psychiatric Illness a Risk Factor for Hyperemesis Gravidarum?

  While the majority of pregnant women experience nausea and/or vomiting during the first trimester of pregnancy, a smaller subset of women — around 1% — experience more severe and intractable vomiting, or hyperemesis gravidarum (HG).  If left untreated, prolonged hyperemesis can lead to weight loss, dehydration, nutrient deficiencies and electrolyte disturbances.   We do […]

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In Brief: High Rates of Marijuana Use in Pregnant Teens

According to data from the 2002-2015 National Survey on Drug Use and Health, the prevalence of marijuana use was 3.8% in pregnant women (n=14,400), compared to 7.5% in nonpregnant women (n=395,600).   The investigators observed that marijuana use was higher in the first trimester (6.4%) than in the second (3.3%) or third (1.8%) trimesters.  Marijuana use […]

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Lamotrigine and Pregnancy: Meta-Analysis Shows No Increase in Risk for Malformations

  Maintenance treatment with a mood stabilizer during pregnancy can significantly reduce the risk of relapse in women with bipolar disorder; however, many of the mood stabilizers commonly used in this setting, including lithium and valproic acid, carry some degree of teratogenic risk. In contrast, lamotrigine (Lamictal) appears to be a much safer option for […]

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Do DHA Supplements Make Babies Smarter? Yes, No, Maybe…

DHA or docosahexaenoic acid is an omega-3 fatty acid which is essential for the growth and development of the brain in infants and is required for maintenance of normal brain function in adults. Based on the importance of this nutrient, most infant formulas now contain DHA.  While infants can make DHA from other (“essential”) fatty […]

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Stimulants In Pregnancy and Increased Risk of Gestational Hypertension

  Our group has noted that we are seeing an increase in the number of consultations for women treated with psychostimulants in combination with an antidepressant.  The reasons vary.  Some women have depression and comorbid attention-deficit/hyperactivity disorder (ADHD).  Sometimes a psychostimulant is used to manage residual symptoms and side effects, such as fatigue and cognitive […]

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Synthetic Oxytocin and Its Effect on Postpartum Mood and Anxiety

Often referred to as the “hormone of love,” oxytocin plays an important role in childbirth, maternal behavior, lactation, social affiliation, and sexual pleasure.  Levels of oxytocin, a neuropeptide produced by the hypothalamus and released into the bloodstream via the pituitary gland, rise around the time of delivery.   These levels remain high after delivery, specifically increasing […]

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Is It Safe During Pregnancy? There’s An App for That

  January was Birth Defects Prevention Month, and MotherToBaby launched a free app  designed to provide evidence-based information to pregnant and breastfeeding women. There is Information on a broad range of medications, some herbal remedies, maternal illness, infections and vaccines, alcohol and other substances, occupational exposures, and other exposures (including things like lead, hair dye). […]

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Credit: Pregnant Woman from Wikimedia Commons

The 50-year Quest for Better Pregnancy Data

The following post was first published in OB/GYN News. Please see our OB/GYN News archives here. Publish date: November 1, 2016 By: Gerald G. Briggs, BPharm, FCCP, Christina Chambers, PhD, MPH, Lee S. Cohen, MD, & Gideon Koren, MD Editor’s note: As Ob.Gyn. News celebrates its 50th anniversary, we wanted to know how far the medical community has come in identifying and […]

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The US Opioid Epidemic:  More US Infants Born With Drug Dependence

Over the last week, there have been quite a few articles in the press detailing the increase in opioid use in the United States, focusing the impact of this epidemic on infants and children. According to a study published this week in JAMA Pediatrics, researchers tracked newborns treated for opioid-related complications over the past 10 […]

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Another Medication for Pregnancy-Related Nausea and Vomiting

The US Food and Drug Administration (FDA) has approved another medication for the management of pregnancy-related nausea and vomiting.  It is not really a new medication but is similar to Diclegis, a combination doxylamine succinate and pyridoxine hydrochloride (vitamin B6), which was approved several years ago.   The newly approved medication will be marketed as […]

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