Essential Reads: Are Premenstrual Mood Symptoms a Risk Factor for Suicide?
Women with premenstrual mood disorders face significantly higher risk of suicidal ideation and behavior, highlighting the need for careful assessment and targeted prevention.
In Women with ADHD, Should We Adjust Stimulant Dosage Premenstrually?
This preliminary study demonstrates the potential benefits of increasing the dosage of psychostimulant medication premenstrually in women with ADHD who experience premenstrual worsening of ADHD and mood symptoms.
PMDD Treatment with Serotonin Reuptake Inhibitors: Neuroactive Steroids and GABA May Play a Role
A new study from Miller and colleagues asks whether SRI treatment affects the levels of neuroactive steroids that act at GABA-A receptors.
For PMDD, Does Symptom-Onset Dosing of an SSRI Work?
Symptom-onset dosing with a serotonin reuptake inhibitor for PMDD may have a greater impact on anger/irritability and relationship functioning than other symptoms.
Suicidal Ideation Common in Women Seeking Treatment for Premenstrual Dysphoric Disorder
In this population seeking treatment for PMDD, suicidal ideation is very common, affecting about 40% of the women.
Sepranolone: A New Treatment for PMDD?
In this phase II study, sepranolone 10 mg administered subcutaneously during the late luteal phase reduced PMDD symptoms more than placebo.
Essential Reads – What’s the Difference Between PME and PMDD? How Should We Treat PME?
About 60% of women with mood disorders experience premenstrual exacerbation or PME of their mood during the premenstrual phase of their cycle.
Essential Reads: Is PMDD a Risk Factor for Postpartum Depression?
Some, but not all, studies suggest that PMDD is a risk factor for postpartum depression.
Essential Reads:Â Investigational Treatment of Depressive Disorders With Neuroactive Steroids: Potential Implications for PMDD
Neuroactive steroids, derivatives of allopregnanolone, may be effective for the treatment of premenstrual dysphoric disorder.
Are Women with PMDD at Increased Risk for Suicidality?
In a recent meta-analysis, Yan and colleagues looked at the prevalence of suicidal ideation among women diagnosed with PMDD.