Multiple studies have demonstrated that the postpartum period is a time of increased vulnerability in women with bipolar disorder. However, because many of the commonly used mood stabilizers carry some teratogenic risk, many women elect [...]
Given the number of younger women using atypical antipsychotic medications, we need more accurate data regarding the reproductive safety of these medications. To better understand the link between antipsychotic medication and medical conditions associated with [...]
While gabapentin (Neurontin) is now used in a wide variety of clinical settings — for epilepsy, pain management, restless leg syndrome, anxiety, and sleep disturbance – there is relatively little information regarding its reproductive safety. [...]
Over the last few years, we have reported on several studies which have suggested an increased risk of certain types of cardiovascular malformations among children exposed to selective serotonin reuptake inhibitors (SSRIs) during pregnancy. The first reports [...]
Second-generation or “atypical” antipsychotics, such as olanzapine (Zyprexa), aripiprazole (Abilify), and risperidone (Risperdal), are used far more frequently than are the first-generation or “typical” antipsychotics, such as haloperidol (Haldol). This is largely because the newer [...]
Several recent articles suggest that the burden of menopausal symptoms is greater than generally perceived. About 80% of women experience vasomotor symptoms (VMS) – hot flashes and night sweats -- as they transition into the [...]
It is now widely accepted that there is an increased risk for depression among the children of mothers who suffer from depression. Exactly how this vulnerability to depression is transmitted to the child is not precisely understood and is undoubtedly quite complicated. Genetic factors clearly play an important role, but there are other important factors which contribute to the transgenerational transmission of depression. For example, many studies have shown that maternal depression may contribute to parenting styles which increase a child’s likelihood of developing depression later on.
Many studies have examined the association between parental age and psychiatric illness in the children, including autism and schizophrenia. In a recent case-control study from Finland, the authors identified 10,409 individuals with ADHD born between 1991 and 2005 from nationwide population-based registers. Logistic regression was used to examine the association between parental age and ADHD in the offspring, adjusting for potential confounding factors including parental psychiatric history, maternal socioeconomic status, marital status, maternal smoking during pregnancy, number of previous births, and birth weight.
You can find a more recent post on this topic here: Venlafaxine and Duloxetine: Pooled Analysis Shows No Increase in Risk of Malformations We receive a fair number of questions on the use of duloxetine [...]
While we have adequate data to support the use of SSRI antidepressants during pregnancy, there is less data regarding other classes of antidepressants. A new case series documents the outcomes of infants exposed to mirtazapine (Remeron).
