olanzapine

Case Discussion: Management of Severe Nausea and Vomiting in a Pregnant Woman with Bipolar Disorder

This article explores the case of a woman with bipolar disorder who develops HG associated with severe anxiety and sleep disruption, and discusses various treatment options.

By |2025-04-01T08:00:10-04:00April 1st, 2025|Bipolar Disorder, Psychiatric Disorders During Pregnancy|Comments Off on Case Discussion: Management of Severe Nausea and Vomiting in a Pregnant Woman with Bipolar Disorder

New Research from the CWMH: No Increase in Major Malformations in Children with Prenatal Exposure to Olanzapine

No major malformations were associated with olanzapine exposure during the first trimester of pregnancy.

By |2023-03-02T15:52:24-04:00March 1st, 2023|Antipsychotic Medications, Outcomes, Pregnancy & Medications, Research at CWMH, Risk of Malformations|Comments Off on New Research from the CWMH: No Increase in Major Malformations in Children with Prenatal Exposure to Olanzapine

Essential Reads: Atypical Antipsychotics and Breastfeeding

Despite the increasing use of the newer “atypical” or second-generation antipsychotic agents to treat a spectrum of psychiatric disorders, we have relatively little data on the use of these newer atypical agents in breastfeeding women.  

By |2025-12-20T14:15:36-04:00April 7th, 2021|Antipsychotic Medications, Breastfeeding & Medications, Essential Reads, Outcomes|Comments Off on Essential Reads: Atypical Antipsychotics and Breastfeeding

New Research from the CWMH: Prenatal Exposure to Atypical Antipsychotics Does Not Increase Risk of Malformations

The use of the newer “atypical” or second-generation antipsychotic agents continues to increase.  These medications are used to treat a spectrum of psychiatric disorders, including schizophrenia, bipolar disorder, major depression, PTSD and anxiety disorders.  Although [...]

By |2020-11-26T08:33:55-04:00August 23rd, 2016|Antipsychotic Medications, Outcomes, Pregnancy & Medications, Research at CWMH, Risk of Malformations|Comments Off on New Research from the CWMH: Prenatal Exposure to Atypical Antipsychotics Does Not Increase Risk of Malformations

In Brief: Study Finds No Link Between Antipsychotics and Gestational Diabetes

Given the number of younger women using atypical antipsychotic medications, we need more accurate data regarding the reproductive safety of these medications. To better understand the link between antipsychotic medication and medical conditions associated with [...]

By |2020-01-25T23:48:54-04:00May 18th, 2015|Antipsychotic Medications, Outcomes, Pregnancy & Medications, Pregnancy Outcomes|Comments Off on In Brief: Study Finds No Link Between Antipsychotics and Gestational Diabetes

Meta-Analysis: Antipsychotics and Pregnancy Outcomes

Second-generation or “atypical” antipsychotics, such as olanzapine (Zyprexa), aripiprazole (Abilify), and risperidone (Risperdal), are used far more frequently than are the first-generation or “typical” antipsychotics, such as haloperidol (Haldol). This is largely because the newer [...]

By |2015-07-08T11:30:14-04:00May 6th, 2015|Antipsychotic Medications, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on Meta-Analysis: Antipsychotics and Pregnancy Outcomes

Antipsychotics and Pregnancy Part 2: Preliminary Data from the MGH Pregnancy Registry

This is the second part of a two part series on the use of antipsychotic medications during pregnancy.  Read Part 1 here, which reviews data from the Australian antipsychotic registry.

By |2016-03-28T13:23:55-04:00August 6th, 2014|Antipsychotic Medications, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on Antipsychotics and Pregnancy Part 2: Preliminary Data from the MGH Pregnancy Registry

Prevalence and Trends in the Use of Antipsychotic Medications during Pregnancy

Since their introduction in the 1990s, atypical (second-generation) antipsychotics have replaced typical (first generation) antipsychotics as the first-line treatment for schizophrenia and related psychotic disorders. These drugs are widely used by reproductive age women across many other disease states including bipolar disorder, major depression and anxiety disorders as either primary or adjunctive treatments.

By |2024-04-14T16:17:44-04:00June 10th, 2013|Antipsychotic Medications, Pregnancy & Medications|Comments Off on Prevalence and Trends in the Use of Antipsychotic Medications during Pregnancy

Atypical Antipsychotic Medications: What Do We Know About Their Reproductive Safety?

Atypical antipsychotic medications are commonly used for the treatment of schizophrenia and bipolar disorder.  Despite the increasing use of these medications in women of child-bearing age, there is still relatively little data regarding the reproductive safety and long-term neurodevelopmental effects of these medications. A recent study assessed the development of 76 infants with fetal exposure to atypical antipsychotics.

By |2015-08-06T10:39:32-04:00May 15th, 2013|Antipsychotic Medications, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on Atypical Antipsychotic Medications: What Do We Know About Their Reproductive Safety?
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