Clinical Update 2026: Z-Drugs and Pregnancy
Recent studies find no increase in the risk of major malformations with first-trimester Z-drug exposure, although small increases in risk of preterm birth and low birth weight have been reported.
Large Canadian Study Shows Risks Associated with Cannabis Use During Pregnancy
A large cohort study from Canada has observed that cannabis use during pregnancy was associated with increased risk of preterm birth, low birth weight and small-for-gestational age.
Antipsychotic Medication Use in Pregnancy and Risk of Maternal and Neonatal Metabolic Complications
In this retrospective study of Taiwanese women using antipsychotic medications there was no observed increase in risk of metabolic complications.
Buprenorphine or Methadone: Which One is Better for the Treatment of Opioid Use Disorder in Pregnancy?
Treatment with buprenorphine versus methadone during pregnancy is associated with lower risk of preterm birth, low birth weight, small size for gestational age, and NAS.
Cannabis Exposure During Pregnancy Tied to Mental Health Problems in Early Adolescence
Prenatal cannabis exposure was associated with persisting vulnerability to psychopathology throughout early adolescence.
Essential Reads: Obstetric and Perinatal Outcomes among Women with Eating Disorders
Greater attention to eating behaviors and screening eating disorders during pregnancy is the first step in improving outcomes in this population.
Cannabis Use is Legal in Many States, But That Doesn’t Mean It’s Safe to Use During Pregnancy
Heavy cannabis use during pregnancy was associated with increased risk for small for gestational age, preterm birth, low birth weight, and death during the first year of life.
Essential Reads: Lithium and Pregnancy
While the use of lithium has been in decline over the last 20 years, lithium continues to be a useful and highly effective mood stabilizer for women with bipolar disorder, especially those with a history [...]
Lithium and Anticonvulsant Mood Stabilizers: No Higher Risk for Adverse Pregnancy Outcomes
For women with bipolar disorder, choosing whether to maintain or discontinue treatment with a mood stabilizer during pregnancy is challenging. This is a process which requires careful and thoughtful consideration, weighing the risk of adverse [...]
Opioid Exposure During Pregnancy, Long-Term Effects on Children’s Development
According to a recent analysis of national data by the Centers for Disease Control, the number of pregnant women with opioid use disorder (as documented at the time of delivery) more than quadrupled from 1999 [...]