hormone therapy

In Brief: Hormone Therapy for Midlife Women, No Harm but No Benefit for Cognitive Functioning

Early observational studies suggested that hormone replacement therapy (HRT)  may improve cognitive functioning in postmenopausal women; however, larger studies, including the Women’s Health Initiative, have shown that estrogen replacement therapy started in postmenopausal women (65 [...]

By |2021-11-04T08:21:32-04:00August 7th, 2018|Cognition, Hormone Therapy, Menopausal Symptoms, Vasomotor Symptoms|Comments Off on In Brief: Hormone Therapy for Midlife Women, No Harm but No Benefit for Cognitive Functioning

In Brief: Hormone Replacement Has No Impact on Mortality in Women

While there have been concerns regarding the risks associated with prolonged use of hormone replacement, an increasing number of studies suggest that the risk may be relatively low in certain populations and that hormone replacement [...]

By |2021-11-04T08:23:08-04:00September 20th, 2017|Menopausal Symptoms|Comments Off on In Brief: Hormone Replacement Has No Impact on Mortality in Women

NAMS Position Statement on the Use of Hormone Therapy in Women Over 65

Since the Women's Health Initiative (WHI) reported that the risks of menopausal hormone replacement therapy (HRT) outweighed its benefits, there has been a significant reduction in the use of HRT.  However, since that time, studies [...]

By |2015-07-14T17:40:35-04:00July 13th, 2015|Hormone Therapy, Menopausal Symptoms, Treatment, Vasomotor Symptoms|Comments Off on NAMS Position Statement on the Use of Hormone Therapy in Women Over 65

Managing Sleep Problems in Menopausal Women: What Are the Options?

Peri- and post-menopausal women frequently complain of insomnia or poor sleep quality. Sleep disturbance is often attributed to nocturnal hot flashes; however, a recent study from researchers at Wayne State University School of Medicine suggests [...]

By |2025-12-11T09:41:03-04:00June 29th, 2015|Menopausal Symptoms, Sleep Disorders, Treatment|Comments Off on Managing Sleep Problems in Menopausal Women: What Are the Options?

Hormone Replacement Therapy: Some Risk But No Impact on Mortality

While there are concerns regarding the risks associated with prolonged use of hormone replacement, an increasing number of studies suggest that the risk may be relatively low in certain settings.  A study presented this week at the Endocrine Society’s annual meeting which analyzed data from 43 randomized clinical trials suggests that menopausal hormone-replacement therapy does not appear to affect mortality either positively or negatively.

By |2015-08-05T10:19:09-04:00March 12th, 2015|Hormone Therapy, Menopausal Symptoms, Treatment, Vasomotor Symptoms|Comments Off on Hormone Replacement Therapy: Some Risk But No Impact on Mortality

FDA Approves New Hormonal Therapy for Menopausal Symptoms

The US Food and Drug Administration (FDA) has approved a novel estrogen-based drug for women for the treatment of moderate-to-severe vasomotor symptoms and osteoporosis associated with menopause.  Duavee (Wyeth Pharmaceuticals) is a once-a-day tablet containing a combination of conjugated estrogens and bazedoxifene, an estrogen agonist/antagonist.

By |2015-08-04T12:04:14-04:00October 10th, 2013|Medication, Menopausal Symptoms, Treatment, Vasomotor Symptoms|Comments Off on FDA Approves New Hormonal Therapy for Menopausal Symptoms

Does Estrogen Affect Antidepressant Efficacy? Data from the STAR*D Study

We previously reported on studies suggesting estrogen may be helpful for the treatment of depression in peri- and post-menopausal women, either alone or in combination with an antidepressant.  In addition, other studies have suggested that older, postmenopausal women may respond more poorly to antidepressants than premenopausal women. Two recent studies attempt to better understand the impact of reproductive hormones on clinical presentation and treatment response of depression in women.

By |2015-08-06T09:27:57-04:00July 10th, 2013|Depressive Disorders, General, Hormone Therapy, Treatment|Comments Off on Does Estrogen Affect Antidepressant Efficacy? Data from the STAR*D Study

Weight Loss and a Low-Fat Diet Help to Reduce Hot Flashes in Menopausal Women

Various studies have shown that women with a higher body mass index (BMI) or a higher percent of body fat have more frequent or more severe menopausal symptoms.  In a recent study, researchers evaluated the impact of a low-fat diet on vasomotor symptoms in a group of 17,473 postmenopausal women between the ages of 50 and 79.

By |2015-08-12T12:19:50-04:00August 8th, 2012|Alternative & Complementary, Menopausal Symptoms, Prevention, Vasomotor Symptoms|Comments Off on Weight Loss and a Low-Fat Diet Help to Reduce Hot Flashes in Menopausal Women

New Research from the CWMH: Surgically Induced Menopause No Worse than Natural in Terms of Risk for Depression, Anxiety

Each year about 600,000 women in the United States undergo a hysterectomy.  Somewhere between 55% and 80% of these women who also have their ovaries removed along with the uterus—a procedure known as oophorectomy.  After the removal of the ovaries, menopause follows immediately and is associated with a constellation of symptoms including hot flashes and insomnia, as well as depression and anxiety. 

By |2016-03-28T13:02:53-04:00August 2nd, 2012|Depressive Disorders, Menopausal Symptoms, Prevalence & Risk Factors, Research at CWMH|Comments Off on New Research from the CWMH: Surgically Induced Menopause No Worse than Natural in Terms of Risk for Depression, Anxiety
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