You Asked: How Worrisome is the Boxed Warning for the New Postpartum Depression Medication?
The package insert advises patients to avoid driving and other potentially hazardous activities after taking zuranolone.
Essential Reads: SSRI Antidepressants During Pregnancy and Risk of Hypertension, Preeclampsia
There is evidence that depression itself can increase risk for hypertension and preeclampsia. Future studies will help to clarify the complex interaction between depression, SSRI treatment and pre-eclampsia.
Zuranolone for Postpartum Depression: Results from the SKYLARK Study
Zuranolone has antidepressant effects in women with severe PPD, observed as early as 3 days after initiation of treatment. Â
Essential Reads: What is the Best Screening Tool for Depression During Pregnancy?
Many women experience depression during pregnancy. What is the best way to identify these women?
Sage Therapeutics and Biogen Announce Plans to Submit a New Drug Application for Zuranolone to the FDA in 2022
The FDA will review zuranolone for the treatment of depression in the first half of 2022.
Essential Reads: Zuranolone for Postpartum Depression
Zuranolone has antidepressant effects in women with severe PPD, observed as early as 3 days after initiation of treatment. Â
Essential Reads: What is the Best Antidepressant to Use During Pregnancy?
The reality is that most of the antidepressants taken by women today are relatively safe and carry a very low risk to the developing fetus.Â
Taking a Closer Look at Motor Development in Children with Prenatal Exposure to Antidepressants
While we have data to support the use of antidepressants, including the selective serotonin reuptake inhibitors (SSRIs) and the serotonin norepinephrine reuptake inhibitors (SNRIs), during pregnancy, most studies have focused on risk of congenital [...]
Essential Reads: SSRI Antidepressants Do Not Increase Risk of Miscarriage
Many women ask whether taking antidepressants may increase the risk for miscarriage or spontaneous abortion. Some, but not all, studies have demonstrated an increased risk of miscarriage among women who use antidepressants. However, it has [...]
More Data on the Neuroactive Steroid Zuranolone for Postpartum Depression
While we have heard a lot about brexanolone, marketed by Sage Therapeutics as Zulresso, for the treatment of postpartum depression, an oral version of this novel antidepressant – SAGE 217 or zuranolone – has been [...]