Risk of Malformations

Clinical Update 2020: New Data on Duloxetine and Pregnancy

A few weeks ago, we published a clinical update for duloxetine (Cymbalta) and pregnancy, stating that there was little new to report since we last covered the topic in 2015.  It is somewhat amusing [...]

By |2020-08-13T14:28:20-04:00March 6th, 2020|Antidepressants, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on Clinical Update 2020: New Data on Duloxetine and Pregnancy

Clinical Update 2020: Duloxetine and Pregnancy

Women face difficult choices when deciding whether or not to continue psychiatric medications during pregnancy.  For many years, we have typically recommended the older antidepressants, including the selective serotonin reuptake inhibitors or SSRIs such [...]

By |2020-08-10T12:44:33-04:00February 25th, 2020|Antidepressants, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on Clinical Update 2020: Duloxetine and Pregnancy

Preliminary Data Raises Concerns About Modafinil Use in Pregnancy

Modafinil (brand name Provigil) is a wake-promoting agent which is used to treat sleepiness due to narcolepsy, shift work sleep disorder, or obstructive sleep apnea.  It is also used to in others settings, often [...]

By |2020-11-01T21:53:56-04:00January 31st, 2020|ADHD Medications, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on Preliminary Data Raises Concerns About Modafinil Use in Pregnancy

Interpreting New Data on the Use of Benzodiazepines During Pregnancy

Data regarding the reproductive safety of benzodiazepines has always been somewhat difficult to understand.  While earlier studies suggested an association between prenatal exposure to benzodiazepines and increased risk of cleft lip and palate, more recent [...]

By |2019-12-09T22:36:51-04:00December 10th, 2019|Anti-Anxiety Medications, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on Interpreting New Data on the Use of Benzodiazepines During Pregnancy

Anti-Epileptic Drugs in Reproductive Age Women: Valproic Acid and Topiramate Commonly Used

There have long been concerns regarding the safety of the anticonvulsant valproic acid (Depakote) during pregnancy.  Back in 2009, the American Academy of Neurology and American Epilepsy Society recommended against the use of valproic acid [...]

By |2025-06-26T09:07:43-04:00April 9th, 2019|Anti-Epileptic Drugs, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on Anti-Epileptic Drugs in Reproductive Age Women: Valproic Acid and Topiramate Commonly Used

Hispanic Women at High Risk for Neural Tube Defects, May Not Have Adequate Dietary Folic Acid

Because folate deficiency in pregnant women has been associated with an increased risk of neural tube defects, including anencephaly and spina bifida, it is recommended that all women take folic acid supplements before and during [...]

By |2018-11-08T10:35:34-04:00October 30th, 2018|Psychiatric Disorders During Pregnancy, Risk of Malformations|Comments Off on Hispanic Women at High Risk for Neural Tube Defects, May Not Have Adequate Dietary Folic Acid

Valproic Acid: Highlighting Risk and Modifying Prescribing Patterns in Reproductive Age Women

For clinicians who have not yet discovered the incredibly thoughtful and clinically practical monthly articles from Chittaranjan Andrade in the Journal of Clinical Psychiatry, it’s time to take a look.  (Not only are these articles [...]

By |2019-04-05T08:04:27-04:00July 3rd, 2018|Anti-Epileptic Drugs, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on Valproic Acid: Highlighting Risk and Modifying Prescribing Patterns in Reproductive Age Women

Fluvoxamine and Pregnancy: Is There a Right Choice?

  Every day, we see women in our clinic who are deciding whether to continue a selective serotonin reuptake inhibitor (SSRI) for management of depression or anxiety during pregnancy. As a class, SSRI use during [...]

By |2018-09-10T12:34:17-04:00May 16th, 2018|Antidepressants, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on Fluvoxamine and Pregnancy: Is There a Right Choice?
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