Risk of Malformations

Prescription Opioids During Pregnancy and Risk for Major Malformations

Previous studies have suggested a link between opioid exposure during pregnancy and increased risk of certain major malformations, including neural tube defects.  A recent study from Bateman and colleagues assesses the risk of major malformation [...]

By |2021-03-16T09:24:00-04:00March 16th, 2021|Opioids, Outcomes, Perinatal Substance Use, Pregnancy & Medications, Risk of Malformations|Comments Off on Prescription Opioids During Pregnancy and Risk for Major Malformations

Essential Reads: More Data on ADHD Medications and Pregnancy

Women with attention-deficit/hyperactivity disorder (ADHD) often discontinue psychostimulant  medications during pregnancy, especially if they have milder symptoms.  While this approach makes sense in terms of limiting unnecessary exposures in women with what appears to [...]

By |2021-01-19T10:49:57-04:00January 20th, 2021|ADHD Medications, Essential Reads, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on Essential Reads: More Data on ADHD Medications and Pregnancy

Essential Reads: Mirtazapine (Remeron) and Pregnancy

This is the first installment of a new feature on our website: ESSENTIAL READS This is a kind of shortcut which allows you to find the most relevant reviews and articles in reproductive psychiatry. [...]

By |2020-12-01T17:27:59-04:00December 2nd, 2020|Antidepressants, Essential Reads, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on Essential Reads: Mirtazapine (Remeron) and Pregnancy

Modafinil and Armodafinil During Pregnancy: Data to Suggest Increased Risk of Malformations

As soon as we published this article on the use of modafinil during pregnancy, another study was published which included data on the reproductive safety of modafinil and armodafinil from the US Provigil/Nuvigil Pregnancy [...]

By |2022-01-20T18:11:36-04:00November 4th, 2020|ADHD Medications, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on Modafinil and Armodafinil During Pregnancy: Data to Suggest Increased Risk of Malformations

Study Supporting the Reproductive Safety of Gabapentin During Pregnancy

Gabapentin (Neurontin) is now used in a wide variety of clinical settings — for the treatment of epilepsy, pain management, restless leg syndrome, anxiety, and sleep disturbance.  However, there is relatively little information regarding [...]

By |2020-11-17T15:58:03-04:00October 28th, 2020|Alternative & Complementary, Anti-Anxiety Medications, Anti-Epileptic Drugs, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on Study Supporting the Reproductive Safety of Gabapentin During Pregnancy

New (But Still Not Enough) Data on Modafinil and Pregnancy

Modafinil (brand name Provigil) is a wake-promoting agent which is used to treat sleepiness due to narcolepsy, shift work sleep disorder, or obstructive sleep apnea.  It is also used in other settings, often in [...]

By |2020-11-17T16:01:54-04:00October 20th, 2020|ADHD Medications, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on New (But Still Not Enough) Data on Modafinil and Pregnancy

Assessing the Reproductive Safety of Antidepressants: Can Non-Randomized Studies Provide the Information We Need?

Perinatal psychiatry is a field in which we treat vulnerable patients, a mother and her child, where both the illness we are treating and the treatments we prescribe have the potential to affect the outcome.  [...]

By |2020-09-09T17:43:09-04:00September 3rd, 2020|Antidepressants, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on Assessing the Reproductive Safety of Antidepressants: Can Non-Randomized Studies Provide the Information We Need?

Another Study on Antidepressants and Birth Defects: Does it Change Our Decision-Making?

Prozac (fluoxetine) was the first SSRI or selective serotonin reuptake inhibitor.  Since its release in 1988, we have been gathering data on the reproductive safety of fluoxetine and other SSRIs.  Over the last 32 years, [...]

By |2020-11-26T08:23:09-04:00August 25th, 2020|Antidepressants, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on Another Study on Antidepressants and Birth Defects: Does it Change Our Decision-Making?

Clinical Update 2020: Lamotrigine (Lamictal) and Pregnancy

Clinical Update 2020:  Lamotrigine (Lamictal) and Pregnancy Maintenance treatment with a mood stabilizer during pregnancy can significantly reduce the risk of relapse in women with bipolar disorder; however, many of the mood stabilizers commonly [...]

By |2025-06-26T09:06:58-04:00July 28th, 2020|Anti-Epileptic Drugs, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on Clinical Update 2020: Lamotrigine (Lamictal) and Pregnancy
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