Pregnancy & Medications

Antipsychotics and Pregnancy Part 2: Preliminary Data from the MGH Pregnancy Registry

This is the second part of a two part series on the use of antipsychotic medications during pregnancy.  Read Part 1 here, which reviews data from the Australian antipsychotic registry.

By |2016-03-28T13:23:55-04:00August 6th, 2014|Antipsychotic Medications, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on Antipsychotics and Pregnancy Part 2: Preliminary Data from the MGH Pregnancy Registry

Antipsychotics and Pregnancy Part 1: Preliminary Data from the Australian Registry

This is the first part of a two part series on the use of antipsychotic medications during pregnancy. Atypical antipsychotic medications are commonly used for the treatment of schizophrenia and bipolar disorder. Despite the increasing [...]

By |2014-07-28T10:45:35-04:00July 28th, 2014|Antipsychotic Medications, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on Antipsychotics and Pregnancy Part 1: Preliminary Data from the Australian Registry

SSRI Antidepressants Not Associated with Cardiovascular Defects

Over the last few years, we have reported on several studies which have suggested an  increased risk of certain types of cardiovascular malformations among children exposed to selective serotonin reuptake inhibitors (SSRIs) during pregnancy. The [...]

By |2016-03-28T13:55:55-04:00July 9th, 2014|Antidepressants, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on SSRI Antidepressants Not Associated with Cardiovascular Defects

SSRIs and Chiari Malformations

A recent study from researchers at the University of North Carolina reports that the children of depressed mothers treated with selective serotonin reuptake inhibitors (SSRIs) during pregnancy were more likely to develop Chiari type 1 malformations than were the children of mothers with no history of depression.

By |2014-06-17T10:16:50-04:00June 16th, 2014|Antidepressants, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on SSRIs and Chiari Malformations

Latest News From the National Pregnancy Registry

We would like to thank you for your continuing support of the National Pregnancy Registry for Atypical Antipsychotics (NPRAA) at the Center for Women’s Mental Health at Massachusetts General Hospital. We are grateful for all the referrals made to the Registry as our numbers continue to grow every day. Given the Registry’s successful enrollment, we are pleased to announce our plan to release preliminary data at an upcoming conference in June, the American Society of Clinical Psychopharmacology (ASCP) Annual Meeting.

By |2014-05-09T21:28:52-04:00May 5th, 2014|Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on Latest News From the National Pregnancy Registry

Clinical Update 2014: Use of Methylphenidate During Pregnancy

For women with mild to moderate attention-deficit/hyperactivity disorder (ADHD) symptoms, we frequently recommend discontinuing medication and switching to a non-pharmacologic intervention.  Although these women might experience some decrease in their level of functioning, they typically [...]

By |2017-12-22T14:40:20-04:00March 19th, 2014|ADHD Medications, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on Clinical Update 2014: Use of Methylphenidate During Pregnancy

Good News: New Studies Show No Association Between Antidepressants and Risk of Autism

Two recent epidemiologic studies have demonstrated an association between prenatal exposure to selective serotonin reuptake inhibitor antidepressants (SSRIs) with autism spectrum disorders (ASD; Croen et al 2011, Rai et al, 2013).  One important imitation of these two studies is that parental psychiatric disorder in itself is associated with an increased risk of ASD in the offspring, and these studies could not distinguish between the effects of drug exposure and the consequences of the underlying maternal psychiatric illness.  Two new studies shed light on the association between prenatal antidepressant exposure and risk of autism spectrum disorder in the offspring.

By |2016-10-24T22:39:29-04:00February 5th, 2014|Pregnancy & Medications|Comments Off on Good News: New Studies Show No Association Between Antidepressants and Risk of Autism
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