Ruta Nonacs

About Ruta Nonacs, MD PhD

This author has not yet filled in any details.
So far Ruta Nonacs, MD PhD has created 311 blog entries.

More Data on the Neuroactive Steroid Zuranolone for Postpartum Depression

While we have heard a lot about brexanolone, marketed by Sage Therapeutics as Zulresso, for the treatment of postpartum depression, an oral version of this novel antidepressant – SAGE 217 or zuranolone – has been [...]

By |2026-03-10T12:50:13-04:00September 14th, 2020|Medication, Postpartum Depression, Postpartum Psychiatric Disorders, Treatment|Comments Off on More Data on the Neuroactive Steroid Zuranolone for Postpartum Depression

Clinical Update 2020: Lamotrigine (Lamictal) and Pregnancy

Clinical Update 2020:  Lamotrigine (Lamictal) and Pregnancy Maintenance treatment with a mood stabilizer during pregnancy can significantly reduce the risk of relapse in women with bipolar disorder; however, many of the mood stabilizers commonly [...]

By |2025-06-26T09:06:58-04:00July 28th, 2020|Anti-Epileptic Drugs, Outcomes, Pregnancy & Medications, Risk of Malformations|Comments Off on Clinical Update 2020: Lamotrigine (Lamictal) and Pregnancy

You Asked: Should Women Taking Lamotrigine (Lamictal) Use Higher Dose of Folic Acid When Planning for Pregnancy?

We have really enjoyed our weekly virtual rounds.  It’s been a great opportunity to meet other perinatal psychiatrists in the community, and discussions with new people always brings up interesting clinical questions.  Last week [...]

By |2025-06-26T09:06:59-04:00May 20th, 2020|Anti-Epileptic Drugs, Pregnancy & Medications, Treatment, You Asked|Comments Off on You Asked: Should Women Taking Lamotrigine (Lamictal) Use Higher Dose of Folic Acid When Planning for Pregnancy?

New Study Estimates the Astonishing Cost of Neglected Perinatal Mood and Anxiety Disorders in US Mothers

A recently published article in the American Journal of Public Health has attributed a substantial financial cost to untreated perinatal mood and anxiety disorders among mothers. The study, conducted by researchers with the think [...]

By |2025-12-11T09:48:31-04:00May 13th, 2020|Psychiatric Disorders During Pregnancy|Comments Off on New Study Estimates the Astonishing Cost of Neglected Perinatal Mood and Anxiety Disorders in US Mothers

Development of Zuranolone (SAGE 217) for PPD Will Move Forward

Zuranolone or SAGE-217 is similar to brexanolone (marketed as Zulresso), the medication which was FDA-approved for the treatment of  postpartum depression. Zuranolone is a neurosteroid, an analogue of allopregnanolone, which is a positive allosteric [...]

By |2026-03-10T12:50:14-04:00April 9th, 2020|Medication, Postpartum Depression, Postpartum Psychiatric Disorders, Treatment|Comments Off on Development of Zuranolone (SAGE 217) for PPD Will Move Forward

PCOS Carries Increased Risk for Bipolar Disorder, Risk Reduced with Metformin

Polycystic Ovarian Syndrome (PCOS) is the most common endocrine-related dysfunction in women of reproductive age.  Multiple studies have observed a higher prevalence of psychiatric illness, including depressive disorders, anxiety disorders, and bipolar disorder in [...]

By |2024-04-14T16:08:25-04:00January 29th, 2020|Bipolar Disorder, Infertility and Mental Health, PCOS, Prevalence & Risk Factors|Comments Off on PCOS Carries Increased Risk for Bipolar Disorder, Risk Reduced with Metformin
Go to Top