NPR’s 1A Live Discusses Perinatal Depression and the New Medication Zuranolone
NPR’s 1A Live hosts an episode focusing on perinatal depression, including information on the new medication zuranolone for the treatment of postpartum depression.Â
Essential Reads: Neurodevelopmental Outcomes in Children with Prenatal Exposure to Antiepileptic Drugs
There is a growing body of literature to indicate that exposure to certain antiepileptic drugs, most notably valproic acid (VPA, Depakote) during critical periods of development may be associated with long-lasting neurodevelopmental deficits.
Prevalence of ADHD and Autism Spectrum Disorders in Children with Prenatal Exposure to Antipsychotic Medications
The findings of this study do not suggest that prenatal antipsychotics exposure is associated with increased risk for ADHD, ASD, small for gestational age, or preterm birth.
Essential Reads: Zuranolone for Postpartum Depression
Zuranolone has antidepressant effects in women with severe PPD, observed as early as 3 days after initiation of treatment. Â
Depression During Pregnancy Affect Infant’s Brain Anatomy, But No Change with Prenatal Exposure to SSRIs
Infants exposed to maternal depression during pregnancy had significantly larger subcortical grey matter volumes and smaller midbrain volumes.
Essential Reads: Measuring the Impact of Antenatal Depression on the Fetal Brain Using Neuroimaging
Neuroimaging studies indicate that exposure to antenatal depression may determine risk for later neuropsychiatric illness in the child.
Maternal Self-Efficacy as a Risk Factor for Postpartum Depression and Anxiety
Postpartum depression first gained medical attention in the 1970’s. While postpartum depression is similar to depression occurring at other times in a woman’s life, we have learned over time that many women with what we [...]
Essential Reads: Lithium and Pregnancy
While the use of lithium has been in decline over the last 20 years, lithium continues to be a useful and highly effective mood stabilizer for women with bipolar disorder, especially those with a history [...]
Essential Reads: Using Neuroimaging to Visualize the Impact of Maternal Depression on the Developing Brain
When a woman comes in for a consultation regarding the use of medications during pregnancy, we spend most of our time reviewing the potential risks of exposure to medications during pregnancy. However, we must also [...]
Prenatal Exposure to Valproic Acid Linked to Increased Risk for Autism, ADHD
Prenatal exposure to valproate has been associated with an elevated risk (10%) for a broad range of congenital malformations including neural tube defects, as well as adverse neurodevelopmental sequelae, including lower IQ and developmental delays [...]