Depression During Pregnancy Affect Infant’s Brain Anatomy, But No Change with Prenatal Exposure to SSRIs
Infants exposed to maternal depression during pregnancy had significantly larger subcortical grey matter volumes and smaller midbrain volumes.
Essential Reads: Measuring the Impact of Antenatal Depression on the Fetal Brain Using Neuroimaging
Neuroimaging studies indicate that exposure to antenatal depression may determine risk for later neuropsychiatric illness in the child.
Maternal Self-Efficacy as a Risk Factor for Postpartum Depression and Anxiety
Postpartum depression first gained medical attention in the 1970’s. While postpartum depression is similar to depression occurring at other times in a woman’s life, we have learned over time that many women with what we [...]
Essential Reads: Lithium and Pregnancy
While the use of lithium has been in decline over the last 20 years, lithium continues to be a useful and highly effective mood stabilizer for women with bipolar disorder, especially those with a history [...]
Essential Reads: Using Neuroimaging to Visualize the Impact of Maternal Depression on the Developing Brain
When a woman comes in for a consultation regarding the use of medications during pregnancy, we spend most of our time reviewing the potential risks of exposure to medications during pregnancy. However, we must also [...]
Prenatal Exposure to Valproic Acid Linked to Increased Risk for Autism, ADHD
Prenatal exposure to valproate has been associated with an elevated risk (10%) for a broad range of congenital malformations including neural tube defects, as well as adverse neurodevelopmental sequelae, including lower IQ and developmental delays [...]
Taking a Closer Look at Motor Development in Children with Prenatal Exposure to Antidepressants
While we have data to support the use of antidepressants, including the selective serotonin reuptake inhibitors (SSRIs) and the serotonin norepinephrine reuptake inhibitors (SNRIs), during pregnancy, most studies have focused on risk of congenital [...]
Postpartum Depression: Unipolar or Bipolar?
About 15% of women will experience postpartum depression after the birth of a child. While most of those women will have unipolar depression, a certain number of women will have bipolar depression. At this juncture, [...]
Essential Reads: Screening for Perinatal Anxiety Disorders
Anxiety symptoms are common during pregnancy and the postpartum period. According to a recent meta-analysis from Fawcett and colleagues, about one out of every five women has at least one type of anxiety disorder [...]
Prenatal Valproic Acid (Depakote) Exposure Increases Risk for Neurodevelopmental Disorders
While we have considerable information regarding the teratogenic risk associated with prenatal exposure to various antiepileptic drugs (AEDs), we have considerably less information on the impact of exposure to AEDs on behavioral outcomes in [...]