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Tag Archives | vasomotor symptoms

Neurokinin-3 Receptor Antagonists: A Novel Approach to the Treatment of Menopausal Symptoms

Over the last few years, we have seen a number of articles suggesting that the burden of menopausal symptoms is probably greater than generally perceived.  About 80% of women experience vasomotor symptoms (VMS) – hot flashes and night sweats — as they transition into the menopause.  For most, the symptoms are manageable, but for a […]

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Photo by Christoph Lehmann https://www.flickr.com/photos/grooovy_easy/5255389744/in/photolist-91pfh1-5oVsER-pFpnRy-ec2MCd-gF9N97-5b3Vne-4NFhyn-8iQxd7-dUwWK-99SzT7-oEz9b9-6Bd2RD-64wPBn-bRpiQ6-6pQf1X-6CCqez-a7FBLH-9hhcsM-hhqhvC-Hx3Lu-w8y2T4-qpERyX-5FKSzJ-8MiyXg-2hvEdW-RBDAe-qxxAD4-4PRiP1-nE2Gaf-iGVY57-4VahiX-9DGHg9-r2EXfL-3hshNC-gGgjkR-buckND-jBwuQM-tQZcDc-qUzYP5-82899z-tyamDh-Hx9Ur-ciRYs5-jjzkxT-fp455D-2JrfTi-hy318h-5mZDc7-q61Z2D-dywyCa

Vasomotor Symptoms and the Importance of Maintaining a Healthy Body Weight

  While about 80% of peri- and postmenopausal women have vasomotor symptoms (VMS), such as night sweats and hot flashes, it has been observed that higher body mass index (BMI) and body fat are associated with an increased risk of vasomotor symptoms. Thus, it is reasonable to speculate that weight loss may prevent VMS. In […]

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What Exactly Causes Hot Flashes in Menopausal Women? Researchers Look at Neurokinin B

Perimenopausal vasomotor symptoms are triggered by a fall in circulating levels of estrogen and other sex steroids. It has been hypothesized that thermoregulatory centres in the hypothalamus play a crucial role in mediating the hot flash response. However, exactly how do hormonal changes bring about these changes in the hypothalamus?  If we could understand this […]

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Photo by Christoph Lehmann https://www.flickr.com/photos/grooovy_easy/5255389744/in/photolist-91pfh1-5oVsER-pFpnRy-ec2MCd-gF9N97-5b3Vne-4NFhyn-8iQxd7-dUwWK-99SzT7-oEz9b9-6Bd2RD-64wPBn-bRpiQ6-6pQf1X-6CCqez-a7FBLH-9hhcsM-hhqhvC-Hx3Lu-w8y2T4-qpERyX-5FKSzJ-8MiyXg-2hvEdW-RBDAe-qxxAD4-4PRiP1-nE2Gaf-iGVY57-4VahiX-9DGHg9-r2EXfL-3hshNC-gGgjkR-buckND-jBwuQM-tQZcDc-qUzYP5-82899z-tyamDh-Hx9Ur-ciRYs5-jjzkxT-fp455D-2JrfTi-hy318h-5mZDc7-q61Z2D-dywyCa

Nonhormonal Management of Menopausal Vasomotor Symptoms: 2015 NAMS Position Statement

Since the Women’s Health Initiative (WHI) reported that the risks of menopausal hormone replacement therapy (HRT) outweighed its benefits, there has been a significant reduction in the use of HRT.  However, recent studies have suggested that many peri- and postmenopausal women experience significant symptoms for many years and that these symptoms have a marked impact […]

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Photo by Christoph Lehmann https://www.flickr.com/photos/grooovy_easy/5255389744/in/photolist-91pfh1-5oVsER-pFpnRy-ec2MCd-gF9N97-5b3Vne-4NFhyn-8iQxd7-dUwWK-99SzT7-oEz9b9-6Bd2RD-64wPBn-bRpiQ6-6pQf1X-6CCqez-a7FBLH-9hhcsM-hhqhvC-Hx3Lu-w8y2T4-qpERyX-5FKSzJ-8MiyXg-2hvEdW-RBDAe-qxxAD4-4PRiP1-nE2Gaf-iGVY57-4VahiX-9DGHg9-r2EXfL-3hshNC-gGgjkR-buckND-jBwuQM-tQZcDc-qUzYP5-82899z-tyamDh-Hx9Ur-ciRYs5-jjzkxT-fp455D-2JrfTi-hy318h-5mZDc7-q61Z2D-dywyCa

NAMS Urges Prescribers to Avoid Bioidentical Hormones

According to data presented at the annual meeting of the North American Menopause Society (NAMS)  in Las Vega, a growing number of perimenopausal women are asking their doctors for compounded or bioidentical hormones.  Although bioidentical hormones are touted as being “natural”, they, like synthetic hormones, are manufactured in the laboratory.   Bioidentical hormones are chemically identical […]

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Electroacupuncture Effective for Breast Cancer Treatment-Associated Hot Flashes

A recent study examined the effectiveness of electroacupuncture, in which small electric currents are applied to traditional acupuncture needles, in women with breast cancer treatment-associated hot flashes. 120 women with hot flashes were randomized to weekly electroacupuncture, once-daily gabapentin, sham acupuncture, or placebo for 8 weeks. Hot flashes were assessed using a daily self-reported hot […]

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Photo by Christoph Lehmann https://www.flickr.com/photos/grooovy_easy/5255389744/in/photolist-91pfh1-5oVsER-pFpnRy-ec2MCd-gF9N97-5b3Vne-4NFhyn-8iQxd7-dUwWK-99SzT7-oEz9b9-6Bd2RD-64wPBn-bRpiQ6-6pQf1X-6CCqez-a7FBLH-9hhcsM-hhqhvC-Hx3Lu-w8y2T4-qpERyX-5FKSzJ-8MiyXg-2hvEdW-RBDAe-qxxAD4-4PRiP1-nE2Gaf-iGVY57-4VahiX-9DGHg9-r2EXfL-3hshNC-gGgjkR-buckND-jBwuQM-tQZcDc-qUzYP5-82899z-tyamDh-Hx9Ur-ciRYs5-jjzkxT-fp455D-2JrfTi-hy318h-5mZDc7-q61Z2D-dywyCa

Research Study: Vortioxetine for Perimenopausal and Postmenopausal Women

The menopausal transition is a difficult time for many women.  There is an increased risk of depressive episodes during this transition in the reproductive lifecycle, and the majority of women will experience symptoms related to perimenopause (such as hot flashes, sleep disturbance, and cognitive complaints). Vortioxetine (brand name Brintellix) is a novel antidepressant that was […]

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Photo by Christoph Lehmann https://www.flickr.com/photos/grooovy_easy/5255389744/in/photolist-91pfh1-5oVsER-pFpnRy-ec2MCd-gF9N97-5b3Vne-4NFhyn-8iQxd7-dUwWK-99SzT7-oEz9b9-6Bd2RD-64wPBn-bRpiQ6-6pQf1X-6CCqez-a7FBLH-9hhcsM-hhqhvC-Hx3Lu-w8y2T4-qpERyX-5FKSzJ-8MiyXg-2hvEdW-RBDAe-qxxAD4-4PRiP1-nE2Gaf-iGVY57-4VahiX-9DGHg9-r2EXfL-3hshNC-gGgjkR-buckND-jBwuQM-tQZcDc-qUzYP5-82899z-tyamDh-Hx9Ur-ciRYs5-jjzkxT-fp455D-2JrfTi-hy318h-5mZDc7-q61Z2D-dywyCa

SSRIs for Vasomotor Symptoms and Bone Health

Recent research has indicated that selective serotonin reuptake inhibitors (SSRIs) may be an effective option for the treatment of vasomotor symptoms associated with menopause. However, it has been documented in some recent observational studies that SSRIs are associated with an increased risk of bone loss in older patients (2, 4). Since postmenopausal women are already […]

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In Brief: Some Menopausal Symptoms Worse in Women with Depression

Nearly a third of postmenopausal women experience vaginal changes, including dryness, itching and pain during sex — symptoms related to the declining levels of estrogen occurring during the transition to menopause.  According to a study which included 745 postmenopausal women with vaginal symptoms, it appears that these symptoms may be more disruptive for women who […]

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NAMS Position Statement on the Use of Hormone Therapy in Women Over 65

Since the Women’s Health Initiative (WHI) reported that the risks of menopausal hormone replacement therapy (HRT) outweighed its benefits, there has been a significant reduction in the use of HRT.  However, since that time, studies have suggested that many peri- and postmenopausal women experience significant symptoms for many years and that certain populations of women […]

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