supplements - MGH Center for Women's Mental Health

L-Methylfolate for the Treatment of Depression: Can We Use it During Pregnancy?

Last summer, we posted a blog about using folate to treat (and perhaps prevent) depression in women of childbearing age. Supporting that recommendation are the several reports indicating that people with lower folate levels are at higher risk of major depression or may experience more severe depressive symptoms. Other studies have indicated that in folate-deficient patients, antidepressants may be less effective or may take longer to take effect.

By MGH Center for Women's Mental Health|2018-06-15T10:45:27-04:00March 25th, 2013|Psychiatric Disorders During Pregnancy|1 Comment

Is There a Link Between Vitamin D Deficiency and Antenatal Depression?

Several studies have shown that vitamin D deficiency is associated with depression. A recent study has assessed the relationship between vitamin D levels and risk for antenatal depression in a cohort of African-American women. Vitamin D deficiency is more common among African-American women than in Caucasians. The active form of vitamin D is produced as a byproduct of natural sun exposure. Because women with darker skin have more melanin, which blocks the sun’s rays and affects the skin’s ability to produce the active form of vitamin D, they typically have lower vitamin D levels.

By MGH Center for Women's Mental Health|2015-08-11T09:37:16-04:00November 3rd, 2012|Psychiatric Disorders During Pregnancy|0 Comments

More on Vitamin D and Depression

We have recently written about the link between vitamin D and depression. While several studies have indicated that low vitamin D levels may be associated with depression, we lack randomized, controlled trials assessing the benefits of vitamin D supplements for the treatment (or prevention) of depression. A recent report from the Women's Health Initiative Calcium and Vitamin D Trial included 36,282 women (50 to 80 years of age) who were randomized to receive 400 IU vitamin D (with 1000 mg calcium) or to placebo.

By MGH Center for Women's Mental Health|2020-07-27T12:45:01-04:00September 5th, 2012|Menopausal Symptoms|0 Comments

Folic Acid and Risk of Perinatal Depression: Is There an Association?

Recent reports suggest that people with lower folate levels are at higher risk of major depression or may experience more severe depressive symptoms. Other studies indicate that in folate deficient patients, antidepressants may be less effective or may take longer to take effect. In addition, some clinical trials have shown that folate may have a therapeutic effect on depression, either when taken alone or in combination with an antidepressant.

By MGH Center for Women's Mental Health|2015-08-12T12:25:29-04:00July 25th, 2012|Psychiatric Disorders During Pregnancy|0 Comments

Depression in Women: Is There a Role for Vitamin D?

Sources of vitamin D include sunlight (ultraviolet B, or UVB, rays), dietary intake, and supplements. Sunlight is the main source of human vitamin D. Vitamin D refers to different forms of a steroid hormone. Vitamin D3 (also called 1, 25-dihydroxycholecalciferol or calcitriol) is produced by the body when ultraviolet light (in the form of UV B) interacts with 7-dehydrocholesterol . Vitamin D3 is thought to be more potent than vitamin D2, with D3 and D2 being the two forms of vitamin D contained in supplements.

By MGH Center for Women's Mental Health|2015-08-12T17:00:04-04:00January 24th, 2012|Psychiatric Disorders During Pregnancy|4 Comments

Fenugreek and Breastfeeding

Breastfeeding has been associated with multiple medical and psychological benefits. Women with a strong desire to breastfeed, but with a limited milk supply, are often interested in potential ways to augment their milk production.

By MGH Center for Women's Mental Health|2015-08-12T16:27:11-04:00March 29th, 2010|Breastfeeding and Psychiatric Medications|0 Comments

Omega-3 Fatty Acids for Depression in Women

An ideal treatment for major depressive disorder (MDD) in women would be efficacious, safe, and offer broad health benefits. MDD is prevalent in women of childbearing years, and recent research underscores the risk of recurrence [...]

By MGH Center for Women's Mental Health|2020-12-11T12:39:30-04:00June 19th, 2009|Postpartum Psychiatric Disorders, Psychiatric Disorders During Pregnancy|1 Comment

Use of Complementary and Alternative Medicines for Menopausal Hot Flashes

Approximately seventy percent of all women experience hot flashes and/or night sweats (also called vasomotor symptoms) during the menopause transition (Stearns et al. 2002). Until recently, estrogen therapy was the treatment of choice for most women who sought treatment for hot flashes. Since the results of the Women's Health Initiative in 2002 noted risks of prolonged use of hormone therapy in older postmenopausal women (Roussouw et al. 2002), many women pursue other treatments for their hot flashes, including over-the-counter complementary and alternative medicines (CAMs), including soy isoflavones, black cohosh, and omega-3 fatty acids. However, there is limited evidence to support the use of these treatments for hot flashes to date.

By MGH Center for Women's Mental Health|2015-08-12T14:41:43-04:00May 29th, 2009|Menopausal Symptoms|3 Comments

Folic Acid Supplementation is Recommended for All Women Taking Anticonvulsants and Planning Pregnancy

Given recent discussions within our group and with our colleague, Lewis Holmes, MD, chief of the Genetics and Teratology Unit at Massachusetts General Hospital for Children and director of the North American AED (Antiepileptic Drug) Pregnancy Registry, I wanted to expand upon a previous blog post. In the initial post, I wrote that women who take certain medications, like mood stabilizers or antiepileptic drugs, are advised to take increased doses of folic acid before pregnancy and throughout pregnancy.

By MGH Center for Women's Mental Health|2015-08-12T11:51:27-04:00November 11th, 2008|Psychiatric Disorders During Pregnancy|3 Comments

St. John’s Wort: Is it Safe for Pregnancy?

St. John's wort (Hypericum perforatum) is an herbal preparation which has been shown, in some studies, to be effective for the treatment of mild to moderate depressive symptoms. St. John's wort is now one of the most commonly used herbal products in the United States and is widely used in Europe.

By MGH Center for Women's Mental Health|2015-08-11T14:14:20-04:00August 5th, 2008|Psychiatric Disorders During Pregnancy|0 Comments